Protein Alignment AstA-R2 and prlhr2a

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001034615.1
• Gene: prlhr2a / 654782
• ZFINID: ZDB-GENE-060209-1
• Length: 370
• Species: Danio rerio
• Alignment Length: 355
• Identity: 107/355 - (30%)
• Similarity: 173/355 - (48%)
• Gaps: 41/355 - (11%)

  Fly     1 MENTTM-------LANISLNATRNEENITSFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLL 58
            :||.||       :..:.|.:|.:.:....|...|   .:....|.|:. .:.::.:.|.|||.|
Zfish    18 LENVTMENSSVGRIYEVMLQSTNSTKRNPQFVGVE---LLQSFKPLIIP-CYALVVLVGVFGNYL 78

  Fly    59 VILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFT-ATDYMVYYWPYGRFWCRSVQYLIVVTA 122
            ::.|:.....|.:.||..|.|||.:|::....|:||| |..:....|.:|||.|..|..:..||.
Zfish    79 LLYVICQTKKMHNVTNFFIGNLAFSDMLMCATCVPFTLAYAFNPRGWVFGRFMCYLVFLIQPVTV 143

  Fly   123 FASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTL----WIVVLVVSVPVAFTHDVVVDY 183
            :.|::||..:.:||:.|.|||::.|      |:::|...|    ||:...:..| |..|...|::
Zfish   144 YVSVFTLTAIGVDRYYATVHPLKKR------ISVLACTYLLSGIWILSCGLVAP-AVAHTYHVEF 201

  Fly   184 DAKKNITYGMCTFTTNDF-LGPRTYQV-----TFFISSYLLPLMIISGLYMRMIMRLWR---QGT 239
               |:..:.:|    .:| :|....::     |.|| :|:|||..:...|:.:.::|..   .|.
Zfish   202 ---KDEGFTIC----EEFWMGQEKERLAYAYSTLFI-TYVLPLSALCISYLCISVKLRNCVVPGH 258

  Fly   240 GVRMSKESQRGRKRVT-RLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQTLAY 303
            ..:...|:||.|||.| |||.:||.||...|||:.:..:|:.:|:...:....|:||:.......
Zfish   259 RTQSQAEAQRARKRKTFRLVSLVVAAFGICWLPISVFNVLRDIDIDLIDKRYFLLIQLLCHLCGM 323

  Fly   304 SSSCINPLLYAFLSENFRKAFYKAVNCSSR 333
            ||||.||.|||:|.:.||....|...|..|
Zfish   324 SSSCCNPFLYAWLHDRFRAELRKMFTCHRR 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	95/299 (32%)
		TM helix 1	40..66	CDD:320224	7/25 (28%)
		TM helix 2	73..99	CDD:320224	12/26 (46%)
		TM helix 3	111..141	CDD:320224	10/29 (34%)
		TM helix 4	153..173	CDD:320224	5/23 (22%)
		TM helix 5	204..233	CDD:320224	8/33 (24%)
		TM helix 6	249..279	CDD:320224	15/30 (50%)
		TM helix 7	292..317	CDD:320224	12/24 (50%)
prlhr2a	NP_001034615.1	7tmA_PrRP_R	59..344	CDD:320516	96/300 (32%)
		TM helix 1	60..86	CDD:320516	7/26 (27%)
		TM helix 2	93..118	CDD:320516	11/24 (46%)
		TM helix 3	132..162	CDD:320516	10/29 (34%)
		TM helix 4	173..194	CDD:320516	6/21 (29%)
		TM helix 5	220..249	CDD:320516	8/29 (28%)
		TM helix 6	269..299	CDD:320516	14/29 (48%)
		TM helix 7	312..337	CDD:320516	12/24 (50%)