Protein Alignment AstA-R2 and oprm1

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_571782.2
• Gene: oprm1 / 65088
• ZFINID: ZDB-GENE-010125-1
• Length: 382
• Species: Danio rerio
• Alignment Length: 353
• Identity: 112/353 - (31%)
• Similarity: 179/353 - (50%)
• Gaps: 41/353 - (11%)

  Fly     1 MENT------------TMLANISL---NATRNE--ENITSFFTDEEWLAINGTLPWIVGF----F 44
            ||||            .|::|.|:   |.:.:.  .|:.|...|........:.|.||..    .
Zfish     2 MENTGNISDLLYALSNPMVSNSSIFCRNFSNSSGLVNMNSSVCDRTPELDKSSTPVIVAIIITAL 66

  Fly    45 FGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRF 109
            :.::.:.|..||:||:.|::....|::.||:.|.|||.||.: ....:||.:.:|::..||:|..
Zfish    67 YSIVCVMGLVGNVLVMYVIIRYTKMKTATNIYIFNLALADSL-ATSTLPFQSVNYLMGTWPFGDE 130

  Fly   110 WCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVA 174
            .|:.|..:.....|.||:||..||:||::||.||:::...||.....|..|..||:...:.:||.
Zfish   131 LCKIVMSIDYYNMFTSIFTLTTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVM 195

  Fly   175 FTHDVVVDYDAKKNITYGMCTFTTNDFLGPRTY-----QVTFFISSYLLPLMIISGLYMRMIMRL 234
            .......|..:...|.   ||..   |..|..|     ::..||.::::|::||:..|..||:||
Zfish   196 VMASTTSDLHSNGIID---CTLL---FPHPSWYWENLLKICVFIFAFIMPVLIITVCYGLMILRL 254

  Fly   235 WRQGTGVRM---SKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQV 296
                ..|||   |||..|..:|:||:|:|||..|...|.|:.:.:::|:|..| .|:|.:.:...
Zfish   255 ----KSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIFVIIKALVTI-PNSLLQTITWH 314

  Fly   297 TAQTLAYSSSCINPLLYAFLSENFRKAF 324
            ....|.|::||:||:|||||.|||::.|
Zfish   315 FCIALGYTNSCLNPVLYAFLDENFKRCF 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	99/296 (33%)
		TM helix 1	40..66	CDD:320224	8/29 (28%)
		TM helix 2	73..99	CDD:320224	10/25 (40%)
		TM helix 3	111..141	CDD:320224	12/29 (41%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	10/33 (30%)
		TM helix 6	249..279	CDD:320224	11/29 (38%)
		TM helix 7	292..317	CDD:320224	10/24 (42%)
oprm1	NP_571782.2	7tmA_Mu_opioid_R	61..342	CDD:320218	97/292 (33%)
		TM helix 1	62..88	CDD:320218	6/25 (24%)
		TM helix 2	95..121	CDD:320218	10/26 (38%)
		TM helix 3	132..162	CDD:320218	12/29 (41%)
		TM helix 4	174..196	CDD:320218	6/21 (29%)
		TM helix 5	224..253	CDD:320218	8/28 (29%)
		TM helix 6	268..298	CDD:320218	11/29 (38%)
		TM helix 7	310..335	CDD:320218	10/24 (42%)