Protein Alignment AstA-R2 and aplnr

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001027492.1
• Gene: aplnr / 613084
• XenbaseID: XB-GENE-6456077
• Length: 364
• Species: Xenopus tropicalis
• Alignment Length: 354
• Identity: 96/354 - (27%)
• Similarity: 170/354 - (48%)
• Gaps: 61/354 - (17%)

  Fly    25 FTDEEWLAINGTLPWIVGF-----FFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAAD 84
            :|:|..|.......|.:.:     |:.::.:.|..||.:||..|......|.:.:..|.|||.||
 Frog    19 YTNESGLPPCDETDWDLSYSLLPVFYMIVFVLGLSGNGVVIFTVWKAKPKRRSADTYIGNLALAD 83

  Fly    85 LMFVILCIPFTAT-DYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRM 148
            |.||: .:|..|| ..:.::||:|...|:...||:::..|||::.|..:|.||:||:||.:.|..
 Frog    84 LAFVV-TLPLWATYTALGFHWPFGSALCKLSSYLVLLNMFASVFCLTCLSFDRYLAIVHSLSSAK 147

  Fly   149 MRTENITLIAIVTLWIVVLVVSVPVAFTHD-------VVVDYD-----AKKNITY---GMCTFTT 198
            :|:.:..|:::..:|:...::::|.....|       .:.|.|     :|:|..:   |:...||
 Frog   148 LRSRSSILVSLAVIWLFSGLLALPSLILRDTRVEGNNTICDLDFSGVSSKENENFWIGGLSILTT 212

  Fly   199 NDFLGPRTYQVTFFISSYLLPLMIISGLYM----RMIMRLWRQGTGVRMSKESQRGRKRVTRLVV 259
                          :..:||||::::..|.    ::.|..      ..:.||.|: :||:.::::
 Frog   213 --------------VPGFLLPLLLMTIFYCFIGGKVTMHF------QNLKKEEQK-KKRLLKIII 256

  Fly   260 VVVIAFASLWLPVQLILLLKSLDV---IETNTLTKLVI---QVTAQTLAYSSSCINPLLYAFLSE 318
            .:|:.||..|||..::..:..||:   :|.:..|:.:|   ...|..|||.:||:||.||||...
 Frog   257 TLVVVFAICWLPFHILKTIHFLDLMGFLELSCSTQNIIVSLHPYATCLAYINSCLNPFLYAFFDL 321

  Fly   319 NFRK------AFYKAVNCSSRYQNYTSDL 341
            .||.      .|.||:  .....|.:|.|
 Frog   322 RFRSQCFFFFGFKKAL--QGHLSNTSSSL 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	87/321 (27%)
		TM helix 1	40..66	CDD:320224	7/30 (23%)
		TM helix 2	73..99	CDD:320224	12/26 (46%)
		TM helix 3	111..141	CDD:320224	12/29 (41%)
		TM helix 4	153..173	CDD:320224	2/19 (11%)
		TM helix 5	204..233	CDD:320224	5/32 (16%)
		TM helix 6	249..279	CDD:320224	8/29 (28%)
		TM helix 7	292..317	CDD:320224	13/27 (48%)
aplnr	NP_001027492.1	7tmA_Apelin_R	28..327	CDD:341340	87/320 (27%)
		TM helix 1	39..65	CDD:341340	7/25 (28%)
		TM helix 2	72..97	CDD:341340	12/25 (48%)
		TM helix 3	110..140	CDD:341340	12/29 (41%)
		TM helix 4	153..174	CDD:341340	3/20 (15%)
		TM helix 5	204..233	CDD:341340	8/42 (19%)
		TM helix 6	246..276	CDD:341340	9/30 (30%)
		TM helix 7	295..320	CDD:341340	12/24 (50%)