Protein Alignment AstA-R2 and ACKR3

DIOPT Version :9

• Sequence 1: NP_001263042.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_064707.1
• Gene: ACKR3 / 57007
• HGNCID: 23692
• Length: 362
• Species: Homo sapiens
• Alignment Length: 332
• Identity: 79/332 - (23%)
• Similarity: 138/332 - (41%)
• Gaps: 45/332 - (13%)

  Fly    25 FTDEEW-----------------LAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMRST 72
            |:|..|                 :.....|.:.:.|.:..|.:.|...|.:|:.|.:........
Human    14 FSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYD 78

  Fly    73 TNLMIVNLAAADLMFVILCIPFTATDYMVY-YWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDR 136
            |:..|:|||.||| :|:|.||......:.: .||.|...|:....:..:..|.||:.|..||:||
Human    79 THCYILNLAIADL-WVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLFGSIFFLTCMSVDR 142

  Fly   137 FLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTND- 200
            :|::.:...:...|.:.:..:..:.:|::...||:|..:....|.  .|..|.||....:..:.
Human   143 YLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVT--SASNNETYCRSFYPEHSI 205

  Fly   201 ---FLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQRGRKRVTRLVVVVV 262
               .:|.....|   :..:.:|..||:..|.     |..:.......:|....||.:...|||.:
Human   206 KEWLIGMELVSV---VLGFAVPFSIIAVFYF-----LLARAISASSDQEKHSSRKIIFSYVVVFL 262

  Fly   263 IAFASLWLPVQLILLLKSLDVIETNTLT-KL------VIQVTAQTLAYSSSCINPLLYAFLSENF 320
            :.    |||..:.:||....::.....| :|      .:.|| |.|:....|:||:||:|::.|:
Human   263 VC----WLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVT-QCLSLVHCCVNPVLYSFINRNY 322

  Fly   321 RKAFYKA 327
            |....||
Human   323 RYELMKA 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_001263042.1	7tm_4	47..>164	CDD:304433	31/117 (26%)
		7tm_1	55..313	CDD:278431	65/269 (24%)
ACKR3	NP_064707.1	7tm_1	62..315	CDD:278431	65/268 (24%)
		C-terminal cytoplasmic tail	324..362		2/6 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147277
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840