Protein Alignment AstA-R2 and grpr

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: XP_695673.2
• Gene: grpr / 567289
• ZFINID: ZDB-GENE-081015-4
• Length: 376
• Species: Danio rerio
• Alignment Length: 335
• Identity: 88/335 - (26%)
• Similarity: 163/335 - (48%)
• Gaps: 24/335 - (7%)

  Fly    40 IVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYW 104
            |:...:.::...|..||:.:|.......:||:..||.:.:||..|::.::.|.|..|:.::...|
Zfish    36 IIATVYALLITAGLIGNVTLIRTFCIVKSMRNVPNLFMSSLALGDVLLLVTCAPVDASKFLADEW 100

  Fly   105 PYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVV 169
            .:||..|:.:.::.:.:...|::||..::.||:.|:|.|:..:..:......:...::|::.:|:
Zfish   101 LFGRMGCKLIPFIQLTSVGVSVFTLTALAADRYKAIVKPMDIQSSKASLKVCLRAASIWMLSMVL 165

  Fly   170 SVPVAFTHDVVVDYDAKKNITYGMCT-FTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMR 233
            ::|.|...|:...:..:.|.|:..|. :.....|.|:.:.:..|:..|::||.|||..|:.:...
Zfish   166 AIPEAVFSDLHTFHIPQTNETFKTCAPYPHAGDLHPKIHSMASFLILYIIPLFIISVYYIFIARS 230

  Fly   234 LWRQ--------GTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNT-L 289
            |.:.        .|.:|...||   |.|:.:.|:|.|..||..|||..:|.|.:|....|.:| :
Zfish   231 LIQSANNMPVEGNTHIRRQVES---RMRLAKTVLVFVGLFAICWLPNHVIYLYRSYHYTEVDTSM 292

  Fly   290 TKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKAVNC-----------SSRYQNYTSDLPP 343
            ...:..|.|:.||:::||:||.....||::|||.|.|.:.|           |.|:....|.|..
Zfish   293 AHFIASVCARILAFTNSCVNPFALYLLSKSFRKQFNKQLCCCCPSISLRSQSSRRHNTRLSSLKS 357

  Fly   344 PRKTSCARTS 353
            .:..|.|..|
Zfish   358 TQNHSVASFS 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	78/293 (27%)
		TM helix 1	40..66	CDD:320224	5/25 (20%)
		TM helix 2	73..99	CDD:320224	8/25 (32%)
		TM helix 3	111..141	CDD:320224	7/29 (24%)
		TM helix 4	153..173	CDD:320224	2/19 (11%)
		TM helix 5	204..233	CDD:320224	9/28 (32%)
		TM helix 6	249..279	CDD:320224	12/29 (41%)
		TM helix 7	292..317	CDD:320224	8/24 (33%)
grpr	XP_695673.2	7tm_GPCRs	37..327	CDD:475119	77/292 (26%)
		TM helix 1	37..61	CDD:410628	4/23 (17%)
		TM helix 2	70..92	CDD:410628	7/21 (33%)
		TM helix 3	108..130	CDD:410628	3/21 (14%)
		TM helix 4	153..169	CDD:410628	2/15 (13%)
		TM helix 5	202..225	CDD:410628	7/22 (32%)
		TM helix 6	257..279	CDD:410628	9/21 (43%)
		TM helix 7	295..320	CDD:410628	8/24 (33%)