Protein Alignment AstA-R2 and tacr1b

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001268728.1
• Gene: tacr1b / 564017
• ZFINID: ZDB-GENE-091117-17
• Length: 412
• Species: Danio rerio
• Alignment Length: 353
• Identity: 88/353 - (24%)
• Similarity: 160/353 - (45%)
• Gaps: 57/353 - (16%)

  Fly    39 WIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVY- 102
            |.:.:.  .|.:....||:.||.:::.:..||:.||..:||||.|:...    ..|......:|
Zfish    42 WAIAYC--TIVLVSVVGNITVIWIILAHKRMRTVTNYFLVNLAFAEASM----SAFNTVINFIYA 100

  Fly   103 ---YWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWI 164
               .|.:|..:||...:..:...|||||::..:::||::|::||::.|:...|  |.:.:..:|.
Zfish   101 VHNEWYFGLVYCRFHNFFPIAAVFASIYSMTAIALDRYMAIIHPLQQRLSSAE--TKLVVCVIWA 163

  Fly   165 VVLVVSVPVAFTHDV------VVDYDAKKNIT---YGMCTFTTNDFLGPRTYQVTFFISSYLLPL 220
            :.|:::.|..:....      ||.|     |.   |.|..|       .:||.|...:..|.|||
Zfish   164 LALMLAFPQYYFSSTAQLPGRVVCY-----INWPEYSMWDF-------QKTYYVCVVVLIYFLPL 216

  Fly   221 MIISGLYMRMIMRLWRQ---GTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSL- 281
            :::...|:.:...||..   |......:|....:::|.::::|||..||:.|||..:..::...
Zfish   217 LVMGCAYLVVGCFLWASEIPGDSSDRYREQLIAKRKVVKMMIVVVCTFATCWLPYHVYFIVHQFL 281

  Fly   282 -DVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKAVN---C------------ 330
             .:.|...:.::.:.:  ..||.||:..||::|..|::.||..|.:|.:   |
Zfish   282 PHLFEERYIQQVYLGI--MWLAMSSTMYNPIIYCLLNDRFRAGFQQAFSWCPCVPQGSYEGLELK 344

  Fly   331 SSRY-QNYTSDLPPPR-KTSCARTSTTG 356
            |:|| |...|.....| :|:.:....||
Zfish   345 STRYLQTQASIFRASRMETTVSTVMPTG 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	76/302 (25%)
		TM helix 1	40..66	CDD:320224	5/25 (20%)
		TM helix 2	73..99	CDD:320224	8/25 (32%)
		TM helix 3	111..141	CDD:320224	10/29 (34%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	8/28 (29%)
		TM helix 6	249..279	CDD:320224	9/29 (31%)
		TM helix 7	292..317	CDD:320224	7/24 (29%)
tacr1b	NP_001268728.1	7tm_GPCRs	40..323	CDD:475119	76/302 (25%)
		TM helix 1	42..66	CDD:410628	6/25 (24%)
		TM helix 2	75..97	CDD:410628	7/25 (28%)
		TM helix 3	113..135	CDD:410628	6/21 (29%)
		TM helix 4	156..172	CDD:410628	2/15 (13%)
		TM helix 5	201..224	CDD:410628	7/22 (32%)
		TM helix 6	254..276	CDD:410628	8/21 (38%)
		TM helix 7	291..316	CDD:410628	7/26 (27%)