Protein Alignment AstA-R2 and ackr3b

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001077301.1
• Gene: ackr3b / 561050
• ZFINID: ZDB-GENE-031116-61
• Length: 362
• Species: Danio rerio
• Alignment Length: 346
• Identity: 86/346 - (24%)
• Similarity: 152/346 - (43%)
• Gaps: 65/346 - (18%)

  Fly    12 LNATRNEENIT------SFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMR 70
            ||.:..::|::      |.|:..       .|.:.:...:..:.|.|...|.||:.|.|.....|
Zfish    18 LNFSTLDDNVSHVEVCHSTFSQR-------ALLYALSVLYIFLFIIGLAANALVVWVNVRAERTR 75

  Fly    71 STTNLMIVNLAAADLMFVILCIPFTATDYM-VYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSI 134
            ..|:|.|:|||.|||. |:..:|.:.:..: :.:||:|...|:....:..|..|:||:.|..||:
Zfish    76 YETHLYILNLAIADLC-VVATLPVSISSLLQLGHWPFGGAMCKITHLIFSVNLFSSIFFLTCMSV 139

  Fly   135 DRFLAVV---HPIRSRMMRTENITLIAIVTLWIVVLVVSVPV-------------AFTHDVVVDY 183
            ||:|:|.   .....|..||..|..:.:   |::.|:.::|.             |.....|...
Zfish   140 DRYLSVKLFGDTPSQRKRRTRQIICVGV---WLLALIAALPEIYFLQAEKSDHSDAIVCKAVYPV 201

  Fly   184 DAKKNITYGMCTFTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQ 248
            ::.|..|.|:              |::||:..:.:|..:|:..|:.:       ...:..|.:.:
Zfish   202 ESMKEWTVGI--------------QMSFFMLGFAIPFPVIAVFYVLL-------ANTIHPSVDQE 245

  Fly   249 RGRKRVTR-LVVVVVIAFASLWLPVQLILLLKS---LDVIETN-TLTKLVIQVTAQTLAYS--SS 306
            |   |::| |:...::.|...|||....|||.:   |:|:..| ||...:......|..:|  ..
Zfish   246 R---RISRHLIFTYIVVFLVCWLPYHGALLLDTLAFLNVLPFNCTLENALYAALHLTQCFSLFHC 307

  Fly   307 CINPLLYAFLSENFRKAFYKA 327
            |.||::|.|:::|:|....||
Zfish   308 CANPIIYNFINKNYRYDLMKA 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	78/308 (25%)
		TM helix 1	40..66	CDD:320224	7/25 (28%)
		TM helix 2	73..99	CDD:320224	11/25 (44%)
		TM helix 3	111..141	CDD:320224	11/29 (38%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	6/28 (21%)
		TM helix 6	249..279	CDD:320224	10/30 (33%)
		TM helix 7	292..317	CDD:320224	7/26 (27%)
ackr3b	NP_001077301.1	7tmA_ACKR3_CXCR7	44..325	CDD:320118	78/308 (25%)
		TM helix 1	45..71	CDD:320118	7/25 (28%)
		TM helix 2	78..102	CDD:320118	11/24 (46%)
		TM helix 3	116..146	CDD:320118	11/29 (38%)
		TM helix 4	159..180	CDD:320118	5/23 (22%)
		TM helix 5	208..235	CDD:320118	8/47 (17%)
		TM helix 6	244..274	CDD:320118	10/32 (31%)
		TM helix 7	293..318	CDD:320118	7/24 (29%)