Protein Alignment AstA-R2 and npffr1l1

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001165167.1
• Gene: npffr1l1 / 559950
• ZFINID: ZDB-GENE-091118-18
• Length: 398
• Species: Danio rerio
• Alignment Length: 380
• Identity: 114/380 - (30%)
• Similarity: 188/380 - (49%)
• Gaps: 52/380 - (13%)

  Fly     5 TMLANISLNATRNEENIT--SFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNN 67
            ||..|.|. |..:.:|.|  .::.....:|::..|.:::.....|:      ||.||.|||:.|.
Zfish     3 TMTLNHSA-ANLSWQNCTLLPYYIHSAGMAVSYILSYLLVLLLCVV------GNGLVCLVVIRNR 60

  Fly    68 NMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLM 132
            ||||.|||.|:|||.:||:..|.|:|.|..|.::..||:.:..|.....:..::..||::|||.:
Zfish    61 NMRSVTNLFILNLAVSDLLVGIFCVPTTLIDSLISGWPFSQITCTMSNLVQGMSVSASVFTLVAI 125

  Fly   133 SIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFT 197
            ::|||..:|:|...|:...  ..|.|||.:|::...:..|.|.|..|:...|         ....
Zfish   126 AVDRFTGIVYPFHHRLRPV--TALFAIVFIWLLAFAIIFPSAATLTVIHLDD---------MYMV 179

  Fly   198 TNDFLGP--------------RTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQ 248
            .||.:.|              |.|....|:..||.||.:||.:|..:..:|   .:.::.::...
Zfish   180 QNDQIYPLFVCFEDWPRADMRRVYTTVIFVHVYLAPLGLISIMYGCIAAKL---SSNLQENRLRS 241

  Fly   249 RGRKRVTRLVVVVVIAFASLWLPVQLILLL---KSLDVIETNTLTKLVIQVTAQTLAYSSSCINP 310
            |.|.:|.:::::|.:.|...|||:..::||   :.||..:.:.|:..:..| |..||:.:|.:||
Zfish   242 RRRMKVIKMLIMVAVLFMVSWLPLWTLMLLTDYQDLDRQQIDFLSSYLFPV-AHWLAFFNSGVNP 305

  Fly   311 LLYAFLSENFRKAFYKAVNC--------SSRYQNYTSDLPPPRKTS-CARTSTTG 356
            ::|.|.:||||:.|..||.|        ..|:.::.  ||||.|.| .:|..|:|
Zfish   306 IIYGFFNENFRRGFQAAVACGFCSSVASEMRHTHFV--LPPPNKVSDGSRGVTSG 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	91/301 (30%)
		TM helix 1	40..66	CDD:320224	8/25 (32%)
		TM helix 2	73..99	CDD:320224	13/25 (52%)
		TM helix 3	111..141	CDD:320224	9/29 (31%)
		TM helix 4	153..173	CDD:320224	5/19 (26%)
		TM helix 5	204..233	CDD:320224	11/42 (26%)
		TM helix 6	249..279	CDD:320224	10/32 (31%)
		TM helix 7	292..317	CDD:320224	9/24 (38%)
npffr1l1	NP_001165167.1	7tm_GPCRs	32..319	CDD:475119	92/307 (30%)
		TM helix 1	34..58	CDD:320647	9/29 (31%)
		TM helix 2	67..89	CDD:320647	11/21 (52%)
		TM helix 3	105..127	CDD:320647	5/21 (24%)
		TM helix 4	148..164	CDD:320647	4/15 (27%)
		TM helix 5	201..224	CDD:320647	9/22 (41%)
		TM helix 6	248..270	CDD:320647	5/21 (24%)
		TM helix 7	287..312	CDD:320647	9/25 (36%)