Protein Alignment AstA-R2 and tacr3l

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001243564.1
• Gene: tacr3l / 559201
• ZFINID: ZDB-GENE-061207-19
• Length: 395
• Species: Danio rerio
• Alignment Length: 342
• Identity: 86/342 - (25%)
• Similarity: 160/342 - (46%)
• Gaps: 67/342 - (19%)

  Fly    13 NATRNEENITSFFTDEEW-LAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLM 76
            |.||   |.|:.|....| :|:     |.|. :..|:|: ..||||:||.:::.:..||:.||..
Zfish     9 NVTR---NFTNQFVQPPWRVAV-----WSVA-YSSVLAV-AVFGNLIVIWIILAHKRMRTVTNYF 63

  Fly    77 IVNLAAADLMFVILCIPFTATDYMVY----YWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRF 137
            ::|||.:|....    .|......:|    .|.:|..:|:...:..|...|||||::..:::||:
Zfish    64 LLNLAFSDASMA----AFNTLINFIYATHGEWYFGEVYCKFHNFFPVTAVFASIYSMTAIAVDRY 124

  Fly   138 LAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTNDFL 202
            :|::||::.|:..|  .|.:.||.:|.:.::::.|                    :|.::|...:
Zfish   125 MAIIHPLKPRLSAT--ATKVVIVCIWALAVILAFP--------------------LCFYSTTRTM 167

  Fly   203 GPRT---------------YQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQ---- 248
            ..||               |.:...:..|:|||:::...|..:.:.||    |..:..:|.
Zfish   168 PRRTICYVAWPRPAEDSFMYHIIVTVLVYMLPLVVMGITYTIVGVTLW----GGEIPGDSSDNYV 228

  Fly   249 ---RGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQTLAYSSSCINP 310
               |.:::|.::::|||:.||..|||..:..::..|:.......:...:.::...||.||:..||
Zfish   229 GQLRAKRKVVKMMIVVVVTFALCWLPYHIYFIVTGLNKRLNKWKSIQQVYLSVLWLAMSSTMYNP 293

  Fly   311 LLYAFLSENFRKAFYKA 327
            ::|..|:..||..|.:|
Zfish   294 IIYCCLNGRFRAGFKRA 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	76/310 (25%)
		TM helix 1	40..66	CDD:320224	9/25 (36%)
		TM helix 2	73..99	CDD:320224	7/25 (28%)
		TM helix 3	111..141	CDD:320224	10/29 (34%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	8/43 (19%)
		TM helix 6	249..279	CDD:320224	10/29 (34%)
		TM helix 7	292..317	CDD:320224	7/24 (29%)
tacr3l	NP_001243564.1	7tm_GPCRs	26..307	CDD:475119	77/317 (24%)
		TM helix 1	28..52	CDD:320669	10/25 (40%)
		TM helix 2	61..83	CDD:320669	6/25 (24%)
		TM helix 3	99..121	CDD:320669	6/21 (29%)
		TM helix 4	142..158	CDD:320669	4/35 (11%)
		TM helix 5	185..208	CDD:320669	5/22 (23%)
		TM helix 6	238..260	CDD:320669	8/21 (38%)
		TM helix 7	275..300	CDD:320669	7/24 (29%)