Protein Alignment AstA-R2 and LOC556532

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: XP_684448.3
• Gene: LOC556532 / 556532
• -ID: -
• Length: 366
• Species: Danio rerio
• Alignment Length: 324
• Identity: 102/324 - (31%)
• Similarity: 180/324 - (55%)
• Gaps: 26/324 - (8%)

  Fly    13 NATRNEENITSFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMI 77
            |.:|.:.|:::....:|.|..:..:..:|.:.  ::.:.|..||.||:.|::....|::.||:.|
Zfish    14 NDSRFQGNLSALDEVDEPLPRSAKITIVVVYL--IVCVVGLVGNCLVMYVIIRYTKMKTATNIYI 76

  Fly    78 VNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVH 142
            .|||.||.: |:..:||..||.::.:||:|...|::|..:.....|.|::||.:||:||::||.|
Zfish    77 FNLALADAL-VLATLPFQGTDVILGFWPFGLPLCKAVVAIDYYNMFTSVFTLTVMSVDRYIAVCH 140

  Fly   143 PIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVV-DYDAKKNITYGMCTFTTNDFLGP-- 204
            |:||..:||.....:..|.:|::...|.:|......|.. |:|..:      |..:..:   |
Zfish   141 PVRSLTVRTPLRAKLINVAVWVLASAVGLPAMIMGQVEKDDHDGAE------CMVSLPE---PRK 196

  Fly   205 ---RTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRM---SKESQRGRKRVTRLVVVVVI 263
               |.:.:..|:.|:|:|::|||..|..|:.||    ..||:   |:|..|..:|:|.:|:.||.
Zfish   197 HWDRVFMMCVFLFSFLIPVLIISVCYGLMVRRL----RSVRVLSGSREKDRNLRRITYMVLSVVA 257

  Fly   264 AFASLWLPVQLILLLKSLDVIETN-TLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYK 326
            ||...|:|||::.|:::|..:|.. :.:.:........|.|::||:||:|||||.|||::.|::
Zfish   258 AFVFCWMPVQVLALIQALGHVELGASQSSMAAMHFCIALGYANSCLNPVLYAFLDENFKRCFHE 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	96/294 (33%)
		TM helix 1	40..66	CDD:320224	7/25 (28%)
		TM helix 2	73..99	CDD:320224	12/25 (48%)
		TM helix 3	111..141	CDD:320224	11/29 (38%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	11/33 (33%)
		TM helix 6	249..279	CDD:320224	13/29 (45%)
		TM helix 7	292..317	CDD:320224	10/24 (42%)
LOC556532	XP_684448.3	7tm_GPCRs	38..319	CDD:475119	96/296 (32%)
		TM helix 1	40..64	CDD:320220	7/25 (28%)
		TM helix 2	73..94	CDD:320220	10/21 (48%)
		TM helix 3	110..132	CDD:320220	6/21 (29%)
		TM helix 4	155..171	CDD:320220	3/15 (20%)
		TM helix 5	200..223	CDD:320220	8/22 (36%)
		TM helix 6	249..271	CDD:320220	10/21 (48%)
		TM helix 7	287..312	CDD:320220	10/24 (42%)