Protein Alignment AstA-R2 and tacr3a

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001243567.1
• Gene: tacr3a / 555482
• ZFINID: ZDB-GENE-090312-106
• Length: 399
• Species: Danio rerio
• Alignment Length: 328
• Identity: 88/328 - (26%)
• Similarity: 167/328 - (50%)
• Gaps: 42/328 - (12%)

  Fly    15 TRNEENITSFFTDE----EW-LAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTN 74
            ::|..|:|..||::    .| :|:     |.|. :..::|| ..||||:|:.:::.:..||:.||
Zfish     4 SQNGSNLTGNFTNQFVQPPWRVAL-----WSVA-YSSILAI-AVFGNLIVMWIILAHKRMRTVTN 61

  Fly    75 LMIVNLAAADLMFVILCIPFTATDYMVYY----WPYGRFWCRSVQYLIVVTAFASIYTLVLMSID 135
            ..::|||.:|....    .|......||.    |.:|..:|:...:..|.:.|||||::..:::|
Zfish    62 YFLLNLAFSDASMA----AFNTLINFVYATHGDWYFGEAYCKFHNFFPVTSVFASIYSMSAIAVD 122

  Fly   136 RFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTND 200
            |::|::||::.|:..|  .|.:.||.:|::.:|::.|:.|..  .:....|:.:.|......:.|
Zfish   123 RYMAIIHPLKPRLSAT--ATKVIIVCIWVLAVVLAFPLCFFS--TIKKLPKRTLCYVAWPRPSED 183

  Fly   201 FLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQ-------RGRKRVTRLV 258
               |..|.:...:..|:|||:::...|..:.:.||    |..:..:|.       |.:::|.:::
Zfish   184 ---PFMYHIIVAMLVYVLPLVVMGINYTIVGLTLW----GGEIPGDSSDNYQGQLRAKRKVVKMM 241

  Fly   259 VVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQV--TAQTLAYSSSCINPLLYAFLSENFR 321
            ::||:.||..|||..:..|:..|:  :.....|.:.|:  :...||.||:..||::|..|:..||
Zfish   242 IIVVVTFAFCWLPYHVYFLVTGLN--KQLARWKFIQQIYLSIMWLAMSSTMYNPIIYCCLNSRFR 304

  Fly   322 KAF 324
            ..|
Zfish   305 AGF 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	80/297 (27%)
		TM helix 1	40..66	CDD:320224	8/25 (32%)
		TM helix 2	73..99	CDD:320224	7/25 (28%)
		TM helix 3	111..141	CDD:320224	10/29 (34%)
		TM helix 4	153..173	CDD:320224	5/19 (26%)
		TM helix 5	204..233	CDD:320224	7/28 (25%)
		TM helix 6	249..279	CDD:320224	10/29 (34%)
		TM helix 7	292..317	CDD:320224	8/26 (31%)
tacr3a	NP_001243567.1	7tm_GPCRs	26..307	CDD:475119	81/304 (27%)
		TM helix 1	28..52	CDD:320669	9/25 (36%)
		TM helix 2	61..83	CDD:320669	6/25 (24%)
		TM helix 3	99..121	CDD:320669	6/21 (29%)
		TM helix 4	142..158	CDD:320669	4/15 (27%)
		TM helix 5	185..208	CDD:320669	5/22 (23%)
		TM helix 6	238..260	CDD:320669	7/21 (33%)
		TM helix 7	275..300	CDD:320669	8/24 (33%)