Protein Alignment AstA-R2 and cysltr1

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001018484.1
• Gene: cysltr1 / 553675
• ZFINID: ZDB-GENE-050522-250
• Length: 342
• Species: Danio rerio
• Alignment Length: 346
• Identity: 92/346 - (26%)
• Similarity: 155/346 - (44%)
• Gaps: 59/346 - (17%)

  Fly    45 FGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYY-----W 104
            :.:|.:.|..||...:.|::......|..::.::||..:||    ||:. |....::||     |
Zfish    22 YSIITVFGLMGNGFALYVLLRTYRQTSAFHIYMLNLGVSDL----LCVS-TLPLRVLYYINKGQW 81

  Fly   105 PYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVV 169
            ..|.|.||...|.:.|..:.|::.::.||..||||:|.|:::..:.||....|..|.:||.:.:.
Zfish    82 NLGDFLCRLSSYALYVNLYCSVFFMMAMSFTRFLAIVFPVQNLRLATEKKAWIVCVCIWIFICMT 146

  Fly   170 SVPVAFT--HDVVVDYDAKKNITYGMCTFTTNDFLGP-------RTYQVTFF--ISSYLLPLMII 223
            |.|...:  |.     |...|        .|..|..|       :...:.:|  :..:::|.::|
Zfish   147 SSPFLLSGQHT-----DPLTN--------KTKCFEPPEKPGSLDKLIMLNYFSLVVGFIIPFLVI 198

  Fly   224 SGLYMRMIMRLWRQGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLP--VQLILLL-----KSL 281
            ...|..::..|.|..:|....:.:   |.:..||::||::||...::|  :|..|.|     ||.
Zfish   199 LLCYAGILRTLLRNTSGANKQRYT---RNKAIRLIIVVMLAFLISFMPYHIQRTLHLHFKSRKSA 260

  Fly   282 DVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFR---KAFYKA-----VNCSSRYQNYT 338
            ...|.|.:.|.|  |....||.::||.:|:||.|..||||   ..|.:|     :....|:...:
Zfish   261 TCEEVNYMQKSV--VITLCLAAANSCFDPMLYFFSGENFRHRLSTFRRASGNAILPHKGRHPLQS 323

  Fly   339 SDLPPPRKT---SCARTSTTG 356
            |  ||...:   ||..::|.|
Zfish   324 S--PPAEDSELQSCNGSNTHG 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	82/304 (27%)
		TM helix 1	40..66	CDD:320224	5/20 (25%)
		TM helix 2	73..99	CDD:320224	7/25 (28%)
		TM helix 3	111..141	CDD:320224	11/29 (38%)
		TM helix 4	153..173	CDD:320224	5/19 (26%)
		TM helix 5	204..233	CDD:320224	5/37 (14%)
		TM helix 6	249..279	CDD:320224	11/36 (31%)
		TM helix 7	292..317	CDD:320224	10/24 (42%)
cysltr1	NP_001018484.1	7tmA_CysLTR1	16..301	CDD:320286	82/301 (27%)
		TM helix 1	16..43	CDD:320286	5/20 (25%)
		TM helix 2	50..75	CDD:320286	7/29 (24%)
		TM helix 3	88..118	CDD:320286	11/29 (38%)
		TM helix 4	130..152	CDD:320286	6/21 (29%)
		TM helix 5	179..208	CDD:320286	4/28 (14%)
		TM helix 6	221..251	CDD:320286	9/32 (28%)
		TM helix 7	269..294	CDD:320286	11/26 (42%)