DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstA-R2 and Galr1

DIOPT Version :9

Sequence 1:	NP_001263042.1	Gene:	AstA-R2 / 43393	FlyBaseID:	FBgn0039595	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_037090.2	Gene:	Galr1 / 50577	RGDID:	2656	Length:	346	Species:	Rattus norvegicus

Alignment Length:	316	Identity:	112/316 - (35%)
Similarity:	171/316 - (54%)	Gaps:	22/316 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 FGVIAITGFFGNLLVILVVVFN--NNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYG 107
            ||:|...|..||.|||.|:..:  ...||||||.|:||:.|||.:::.||||.||.|.:..|..|
  Rat    39 FGLIFAMGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLG 103

  Fly   108 RFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVP 172
            .|.|:.:.|...|:...||:||..||:||::|:||..||..:|.....|:.:..:|.:.:.::.|
  Rat   104 AFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASP 168

  Fly   173 VAFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQ 237
            ||:...:   :....|.|:  |.....:.|..:.|.|..|:..|||||::|...|.:::..|.::
  Rat   169 VAYYQRL---FHRDSNQTF--CWEHWPNQLHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKK 228

  Fly   238 GTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQTLA 302
            ..  .|||:|:..:|:..:.|:|||:.|...|||..:|.|......... |......::||..||
  Rat   229 LK--NMSKKSEASKKKTAQTVLVVVVVFGISWLPHHVIHLWAEFGAFPL-TPASFFFRITAHCLA 290

  Fly   303 YSSSCINPLLYAFLSENFRKAFYKAVNC---------SSRYQNYTSDLPPPRKTSC 349
            ||:|.:||::|||||||||||:.:...|         .::.:| ..|.||  .|:|
  Rat   291 YSNSSVNPIIYAFLSENFRKAYKQVFKCRVCNESPHGDAKEKN-RIDTPP--STNC 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_001263042.1	7tm_4	47..>164	CDD:304433	48/118 (41%)
AstA-R2	NP_001263042.1	7tm_1	55..313	CDD:278431	90/259 (35%)
Galr1	NP_037090.2	7tm_1	49..301	CDD:278431	90/259 (35%)
Galr1	NP_037090.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	326..346		6/21 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	179	1.000	Domainoid score	I3436
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	210	1.000	Inparanoid score	I3578
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1294084at2759
OrthoFinder	1	1.000	-	-		FOG0000972
OrthoInspector	1	1.000	-	-		mtm9131
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1132
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.970