Protein Alignment AstA-R2 and SIFaR

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Alignment Length: 386
• Identity: 111/386 - (28%)
• Similarity: 187/386 - (48%)
• Gaps: 55/386 - (14%)

  Fly     4 TTMLANISLNATRNEENITSFFTDEEWLAINGTLPWIVGF----------------FFGVIAITG 52
            ||.|  ||..|.....|.::.    .|..::|::.:  ||                .:.|:.:.|
  Fly   166 TTSL--ISAAAATKSYNDSAL----RWEQLDGSVDF--GFDPLYRHSLAMSMVYCVAYIVVFLVG 222

  Fly    53 FFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYL 117
            ..||..||.||:....||:.||..|||||.||::.::.|:|.|....:...|..|...|:.|.|:
  Fly   223 LIGNSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFVPWMLGWLMCKFVPYI 287

  Fly   118 IVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVV-- 180
            ..|:..||:|:|:.:|:|||:|:..|::....|...|.:|.|   |::.||.::|.....|:|
  Fly   288 QGVSVAASVYSLIAVSLDRFIAIWWPLKQMTKRRARIMIIGI---WVIALVTTIPWLLFFDLVPA 349

  Fly   181 --VDYDAKKNITYGMCTFTTNDFLGPRTYQVTFF-----ISSYLLPLMIISGLYMRMIMRLWR-- 236
              |..||..: .|....|...:...|.|....:|     ::.||||:.:|:..|:.:.:::..
  Fly   350 EEVFSDALVS-AYSQPQFLCQEVWPPGTDGNLYFLLANLVACYLLPMSLITLCYVLIWIKVSTRS 413

  Fly   237 ---QGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLIL--LLKSLDVI-ETNTLTKLVIQ 295
               :....:|.:..|:.:.:|.:::|.|||.|...|||:.:|.  :....|:. |...:.|.|:.
  Fly   414 IPGESKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPLYVIFARIKFGSDISQEEFEILKKVMP 478

  Fly   296 VTAQTLAYSSSCINPLLYAFLSENFRKAF---YKAVNCSSRYQNY-----TSDLPPPRKTS 348
            | ||.|..|:|||||:||: :::.:|:.|   .|:.:|..|.:.|     .|.....||:|
  Fly   479 V-AQWLGSSNSCINPILYS-VNKKYRRGFAAIIKSRSCCGRLRYYDNVAIASSTTSTRKSS 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	93/317 (29%)
		TM helix 1	40..66	CDD:320224	10/41 (24%)
		TM helix 2	73..99	CDD:320224	12/25 (48%)
		TM helix 3	111..141	CDD:320224	13/29 (45%)
		TM helix 4	153..173	CDD:320224	6/19 (32%)
		TM helix 5	204..233	CDD:320224	9/33 (27%)
		TM helix 6	249..279	CDD:320224	10/31 (32%)
		TM helix 7	292..317	CDD:320224	13/24 (54%)
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	91/301 (30%)
		TM helix 1	210..236	CDD:320124	8/25 (32%)
		TM helix 2	243..269	CDD:320124	12/25 (48%)
		TM helix 3	281..311	CDD:320124	13/29 (45%)
		TM helix 4	322..340	CDD:320124	6/20 (30%)
		TM helix 5	379..404	CDD:320124	7/24 (29%)
		TM helix 6	429..459	CDD:320124	10/29 (34%)
		TM helix 7	474..498	CDD:320124	14/25 (56%)