Protein Alignment AstA-R2 and AstC-R1

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_649040.2
• Gene: AstC-R1 / 40020
• FlyBaseID: FBgn0036790
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 433
• Identity: 126/433 - (29%)
• Similarity: 185/433 - (42%)
• Gaps: 93/433 - (21%)

  Fly     6 MLANISLNATRNEENITSFFTDE---EWLAINGT-----------LP--------------WIVG 42
            |.|:...|||.......|.:|.|   .|::.:.|           ||              ....
  Fly    17 MTADSEANATNWYNTNESLYTTELNHRWISGSSTIQPEESLYGTDLPTYQHCIATRNSFADLFTV 81

  Fly    43 FFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYG 107
            ..:|.:.|.|.|||.|||.||:..:.|::.||:.|:|||.||..|:| .|||......:..|.:|
  Fly    82 VLYGFVCIIGLFGNTLVIYVVLRFSKMQTVTNIYILNLAVADECFLI-GIPFLLYTMRICSWRFG 145

  Fly   108 RFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVP 172
            .|.|::......:|:|.|...|::||.||::||.|||.|...||.:|..:.....|....|:.:|
  Fly   146 EFMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTLHIAKVVSAIAWSTSAVLMLP 210

  Fly   173 VAFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRTYQ----VTFFISSYLL----PLMIISGLYMR 229
            |......|...|   .|.|. |     :.:.|..|:    .||.:.::.|    ||..|...|..
  Fly   211 VILYASTVEQED---GINYS-C-----NIMWPDAYKKHSGTTFILYTFFLGFATPLCFILSFYYL 266

  Fly   230 MIMRLWRQG--TGVRMSKESQRGRKRVTRLVVVVVIAFASLWLP--VQLILLLKSLDVIETNTLT 290
            :|.:|...|  .|.: |||.:|..::|||||:.|:..:...|||  :..:.|:.|.......:..
  Fly   267 VIRKLRSVGPKPGTK-SKEKRRAHRKVTRLVLTVISVYILCWLPHWISQVALIHSNPAQRDLSRL 330

  Fly   291 KLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKAVNC------------------------- 330
            :::|.:....|.||:|.:||:|||||||||||:|:||..|
  Fly   331 EILIFLLLGALVYSNSAVNPILYAFLSENFRKSFFKAFTCMNKQDINAQLQLEPSVFTKQGSKKR 395

  Fly   331 --SSRYQNYTSDLPP---------------PRKTSCARTSTTG 356
              |.|.......:||               ...|:..:|.|||
  Fly   396 GGSKRLLTSNPQIPPLLPLNAGNNNSSTTTSSTTTAEKTGTTG 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	101/296 (34%)
		TM helix 1	40..66	CDD:320224	11/25 (44%)
		TM helix 2	73..99	CDD:320224	13/25 (52%)
		TM helix 3	111..141	CDD:320224	10/29 (34%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	10/36 (28%)
		TM helix 6	249..279	CDD:320224	11/31 (35%)
		TM helix 7	292..317	CDD:320224	11/24 (46%)
AstC-R1	NP_649040.2	7tmA_AstC_insect	78..364	CDD:320222	101/296 (34%)
		TM helix 1	79..105	CDD:320222	11/25 (44%)
		TM helix 2	112..138	CDD:320222	13/26 (50%)
		TM helix 3	149..179	CDD:320222	10/29 (34%)
		TM helix 4	191..213	CDD:320222	5/21 (24%)
		TM helix 5	241..270	CDD:320222	8/28 (29%)
		TM helix 6	287..317	CDD:320222	10/29 (34%)
		TM helix 7	332..357	CDD:320222	11/24 (46%)