Protein Alignment AstA-R2 and oprk1

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001305709.1
• Gene: oprk1 / 360139
• ZFINID: ZDB-GENE-030729-1
• Length: 404
• Species: Danio rerio
• Alignment Length: 337
• Identity: 109/337 - (32%)
• Similarity: 179/337 - (53%)
• Gaps: 37/337 - (10%)

  Fly     1 MENTTMLANIS--LNATRNEENITSFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVV 63
            :.|.|..:.:|  .|::.||    |:.|::|  |::..:| |:...:.|:.:.|..||.||:.|:
Zfish    23 LPNFTWQSAVSDIYNSSLNE----SWTTEQE--AMSPLIP-IITAVYSVVFVVGLVGNCLVMYVI 80

  Fly    64 VFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCR---SVQYLIVVTAFAS 125
            :....|::.||:.|.|||.||.: |...:||.:|||::..||:|...|:   |:.|   ...|.|
Zfish    81 IRYTKMKTATNIYIFNLAVADAL-VTTTMPFQSTDYLLNSWPFGEVVCKVFISIDY---YNMFTS 141

  Fly   126 IYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNIT 190
            |:||.:||:||::||.||:::...||.....|..:.:|::.....:|.     :|:......|.|
Zfish   142 IFTLTMMSVDRYVAVCHPVKALDFRTPMKAKIINILIWVLSSAAGIPA-----MVLGSTQTNNGT 201

  Fly   191 YGMCTFTTNDFLGPRTY-----QVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRM---SKES 247
                |.....|..|..|     ::..||..::.||:||:..|..|::||    ..||:   |:|.
Zfish   202 ----TECALQFPDPYVYWDTLMKICVFIFGFVAPLLIITVCYTLMVLRL----KSVRLLSGSREK 258

  Fly   248 QRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQTLAYSSSCINPLL 312
            .|..:|:||||:|||..|...|.|:.:.:|:|:|......|.:.:........|.|::|.:||:|
Zfish   259 DRNLRRITRLVLVVVAVFVVCWTPIHIFILVKALSHGVPETTSVMAAYFFCVALGYTNSSLNPIL 323

  Fly   313 YAFLSENFRKAF 324
            ||||.|||::.|
Zfish   324 YAFLDENFKRCF 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	97/295 (33%)
		TM helix 1	40..66	CDD:320224	8/25 (32%)
		TM helix 2	73..99	CDD:320224	12/25 (48%)
		TM helix 3	111..141	CDD:320224	13/32 (41%)
		TM helix 4	153..173	CDD:320224	2/19 (11%)
		TM helix 5	204..233	CDD:320224	10/33 (30%)
		TM helix 6	249..279	CDD:320224	13/29 (45%)
		TM helix 7	292..317	CDD:320224	9/24 (38%)
oprk1	NP_001305709.1	7tmA_Kappa_opioid_R	56..335	CDD:320219	98/296 (33%)
		TM helix 1	57..83	CDD:320219	8/25 (32%)
		TM helix 2	90..116	CDD:320219	13/26 (50%)
		TM helix 3	127..157	CDD:320219	13/32 (41%)
		TM helix 4	169..191	CDD:320219	3/26 (12%)
		TM helix 5	216..245	CDD:320219	8/28 (29%)
		TM helix 6	260..290	CDD:320219	13/29 (45%)
		TM helix 7	303..328	CDD:320219	9/24 (38%)