Protein Alignment AstA-R2 and CCKLR-17D3

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Alignment Length: 411
• Identity: 88/411 - (21%)
• Similarity: 156/411 - (37%)
• Gaps: 150/411 - (36%)

  Fly    39 WIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYY 103
            |::. .:.:|.:....||||||..:|.|..||:.||:.::|||.:|::..:||:|.|....::..
  Fly   113 WLIP-SYSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRN 176

  Fly   104 WPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLV 168
            :.:|.|.|:..|:....:...|.:|||.:|.:|:.|:.||:|||..:|.:.....|..:|:..::
  Fly   177 FIFGEFLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGFIWLGGIL 241

  Fly   169 VSVPVAFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRTYQVTF-FISSYL---LPLMIISGLYMR 229
            ...|:|....::      .....|.|  ...:|...:.|::.: .:..:|   |||:::...|:.
  Fly   242 CMTPIAVFSQLI------PTSRPGYC--KCREFWPDQGYELFYNILLDFLLLVLPLLVLCVAYIL 298

  Fly   230 MIMRLWRQGTGVRMSKESQR--------------------------------------------- 249
            :...|:     |.|:|:|.|
  Fly   299 ITRTLY-----VGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNN 358

  Fly   250 ----------------------------------------------------------------- 249
                                                                             
  Fly   359 NGNSEGSAGGGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLE 423

  Fly   250 GRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLV-------IQVTA----QTLAY 303
            .:|||.:::.|:|:.|...|.|:.:|           ||:..|:       :..||    |.|||
  Fly   424 SKKRVVKMLFVLVLEFFICWTPLYVI-----------NTMVMLIGPVVYEYVDYTAISFLQLLAY 477

  Fly   304 SSSCINPLLYAFLSENFRKAF 324
            ||||.||:.|.|::.:||:||
  Fly   478 SSSCCNPITYCFMNASFRRAF 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	86/409 (21%)
		TM helix 1	40..66	CDD:320224	8/25 (32%)
		TM helix 2	73..99	CDD:320224	10/25 (40%)
		TM helix 3	111..141	CDD:320224	9/29 (31%)
		TM helix 4	153..173	CDD:320224	2/19 (11%)
		TM helix 5	204..233	CDD:320224	6/32 (19%)
		TM helix 6	249..279	CDD:320224	10/139 (7%)
		TM helix 7	292..317	CDD:320224	15/35 (43%)
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	86/409 (21%)
		TM helix 1	114..138	CDD:320334	7/24 (29%)
		TM helix 2	147..169	CDD:320334	8/21 (38%)
		TM helix 3	185..207	CDD:320334	5/21 (24%)
		TM helix 4	230..246	CDD:320334	2/15 (13%)
		TM helix 5	274..297	CDD:320334	4/22 (18%)
		TM helix 6	429..451	CDD:320334	6/32 (19%)
		TM helix 7	466..491	CDD:320334	14/24 (58%)