Protein Alignment AstA-R2 and CCKLR-17D1

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Alignment Length: 475
• Identity: 105/475 - (22%)
• Similarity: 175/475 - (36%)
• Gaps: 188/475 - (39%)

  Fly    33 INGTLP-WIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTA 96
            ::..:| |:|. .:..|.:....|||||:|.:|.|..||:.||:.::|||.:|::..:.|:|.|.
  Fly   170 VSADVPIWVVP-CYSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTL 233

  Fly    97 TDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVT 161
            ...::.::.:|...|:.:|:....:...|.:|||.:|.:|:.|:.||:|||..:|.|.....|..
  Fly   234 VGTLLRHFIFGELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAI 298

  Fly   162 LWIVVLVVSVPVAFTHDVV------------------VDYDAKKNI----------------TYG 192
            :|:..||...|:|....::                  ::|:...|:                ||.
  Fly   299 IWLGSLVCMTPIAAFSQLMPTSRPGLRKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYL 363

  Fly   193 MCTFTTNDFLGPRTYQVTFFISS------------------------------YLLP-------- 219
            ..|.|.  ::..|..:...|.||                              .::|
  Fly   364 FITRTL--YVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQ 426

  Fly   220 -----------------LMIISG---------LY------------------------------- 227
                             ..:|||         ||
  Fly   427 HHHHSQYYYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGE 491

  Fly   228 -------MRMIMRLWRQG---------------------TGVRMSKE--SQRGRKRVTRLVVVVV 262
                   ||..|:|.:||                     .|:|.|.|  |...:|||.:::.|:|
  Fly   492 CCSRVHRMRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLV 556

  Fly   263 IAFASLWLPVQLILLLKSLDVIETNTLTKLV-------IQVTA----QTLAYSSSCINPLLYAFL 316
            :.|...|.|:.:|           ||:|.|:       :..|:    |.|||||||.||:.|.|:
  Fly   557 LEFFICWTPLYVI-----------NTMTMLLGPTVYEYVGYTSISFLQLLAYSSSCCNPITYCFM 610

  Fly   317 SENFRKAF---YKAVNCSSR 333
            :.:||:||   :|.:....|
  Fly   611 NASFRRAFVDTFKGMRVCER 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	100/454 (22%)
		TM helix 1	40..66	CDD:320224	9/25 (36%)
		TM helix 2	73..99	CDD:320224	9/25 (36%)
		TM helix 3	111..141	CDD:320224	9/29 (31%)
		TM helix 4	153..173	CDD:320224	5/19 (26%)
		TM helix 5	204..233	CDD:320224	12/130 (9%)
		TM helix 6	249..279	CDD:320224	9/29 (31%)
		TM helix 7	292..317	CDD:320224	14/35 (40%)
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	100/454 (22%)
		TM helix 1	178..202	CDD:410628	8/24 (33%)
		TM helix 2	211..233	CDD:410628	7/21 (33%)
		TM helix 3	249..271	CDD:410628	5/21 (24%)
		TM helix 4	294..310	CDD:410628	4/15 (27%)
		TM helix 5	340..363	CDD:410628	2/22 (9%)
		TM helix 6	549..571	CDD:410628	6/32 (19%)
		TM helix 7	586..611	CDD:410628	13/24 (54%)