Protein Alignment AstA-R2 and Pgr15l

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001100053.1
• Gene: Pgr15l / 296867
• RGDID: 1562685
• Length: 456
• Species: Rattus norvegicus
• Alignment Length: 349
• Identity: 95/349 - (27%)
• Similarity: 170/349 - (48%)
• Gaps: 47/349 - (13%)

  Fly     2 ENTTMLANI---SLN-ATRNEENITSFFTDEEWLAINGTL-PWIVG-----------FFFGVIAI 50
            ||.:.:.:|   |.| .|:|..||:|    .||....||: .|:.|           |.:.||.:
  Rat    24 ENVSWVPSIEDQSCNHTTQNGTNISS----AEWGGPRGTVTKWLGGNPHIMAKIVLTFAYAVIIV 84

  Fly    51 TGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQ 115
            ...|||.||..|.|.:...:.:|.|:|.|||.:|::.::|..||....::...|.:||..|...:
  Rat    85 ISLFGNSLVCQVFVKHKETKKSTGLLIFNLAISDILIILLNSPFALARFLSGQWVFGRIMCHVSR 149

  Fly   116 YLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHD-- 178
            :....:...|..||:.:::||...::||::.|:..::::.::.::  |.:.:.:::|.|...:
  Rat   150 FAQYCSLHVSTLTLMAVAMDRHRVILHPMKPRLTHSQSLFVVGVI--WSIAVFLALPHAIYQNLF 212

  Fly   179 --VVVDYDAKKNITYGMCTFTTNDFLGPRTYQVTF-----FISSYLLPLMIISGLYMRMIMRLWR 236
              |.:|.|.:        ::....|.||.|....:     ||..|:|||::|.|.|..:..|||.
  Rat   213 TLVNMDGDVR--------SYCLPSFPGPSTLVSKYVDLGTFILLYILPLLVIVGTYSHLGKRLWI 269

  Fly   237 QG----TGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVT 297
            |.    ...|......:.||:..|:::::|:.||..|.|:...::|.|...:|.::    ||...
  Rat   270 QNAIGDASARQLMAHYQKRKKSIRMLILIVLVFAVCWFPLNFYVVLISSAGVENDS----VIFYA 330

  Fly   298 AQTLAYSSSCINPLLYAFLSENFR 321
            ....|.||:|.||.:|.:|:.:||
  Rat   331 FHWFAMSSTCYNPFIYCWLNRSFR 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	81/307 (26%)
		TM helix 1	40..66	CDD:320224	11/36 (31%)
		TM helix 2	73..99	CDD:320224	10/25 (40%)
		TM helix 3	111..141	CDD:320224	6/29 (21%)
		TM helix 4	153..173	CDD:320224	1/19 (5%)
		TM helix 5	204..233	CDD:320224	11/33 (33%)
		TM helix 6	249..279	CDD:320224	8/29 (28%)
		TM helix 7	292..317	CDD:320224	9/24 (38%)
Pgr15l	NP_001100053.1	7tmA_GPR83	73..357	CDD:320511	79/296 (27%)
		TM helix 1	74..100	CDD:320511	10/25 (40%)
		TM helix 2	107..132	CDD:320511	10/24 (42%)
		TM helix 3	145..175	CDD:320511	6/29 (21%)
		TM helix 4	186..207	CDD:320511	2/22 (9%)
		TM helix 5	237..266	CDD:320511	9/28 (32%)
		TM helix 6	286..316	CDD:320511	8/29 (28%)
		TM helix 7	325..350	CDD:320511	9/28 (32%)