Protein Alignment AstA-R2 and Npy1r

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001106828.1
• Gene: Npy1r / 29358
• RGDID: 3198
• Length: 382
• Species: Rattus norvegicus
• Alignment Length: 372
• Identity: 95/372 - (25%)
• Similarity: 188/372 - (50%)
• Gaps: 37/372 - (9%)

  Fly     1 MENTTMLANISLNATRNEENITSFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVF 65
            :||.::..|:|.|:.     ..:|..|:..|.:  .:.:.:...:|.:.|.|..|||.:|::::.
  Rat     9 VENYSVHYNVSENSP-----FLAFENDDCHLPL--AVIFTLALAYGAVIILGVSGNLALIIIILK 66

  Fly    66 NNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLV 130
            ...||:.||::||||:.:||:..::|:|||....::.:|.:|...|:...::..|:...||::||
  Rat    67 QKEMRNVTNILIVNLSFSDLLVAVMCLPFTFVYTLMDHWVFGETMCKLNPFVQCVSITVSIFSLV 131

  Fly   131 LMSIDRFLAVVHPIRSRMMRTEN-ITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYG-- 192
            |::::|...:::|   |..|..| ...|.|..:|::.:..|:|... :.::.| :..:|::..
  Rat   132 LIAVERHQLIINP---RGWRPNNRHAYIGITVIWVLAVASSLPFVI-YQILTD-EPFQNVSLAAF 191

  Fly   193 ----MC--TFTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGT---GVRMSKESQ 248
                :|  .|.::..  ..:|.....:..|..||..|...|.::.:||.|:..   .:|.||...
  Rat   192 KDKYVCFDKFPSDSH--RLSYTTLLLVLQYFGPLCFIFICYFKIYVRLKRRNNMMDKIRDSKYRS 254

  Fly   249 RGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLD--VIET--NTLTKLVIQVTAQTLAYSSSCIN 309
            ...||:..:::.:|:|||..|||:.:...:...:  :|.|  :.|..|:..:||..    |:|:|
  Rat   255 SETKRINVMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMI----STCVN 315

  Fly   310 PLLYAFLSENFRK---AFYKAVNCSSRYQNYTSDLPPPRKTSCARTS 353
            |:.|.||::||::   .|:...:..||..:|.:.......|..::||
  Rat   316 PIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTS 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	80/303 (26%)
		TM helix 1	40..66	CDD:320224	7/25 (28%)
		TM helix 2	73..99	CDD:320224	12/25 (48%)
		TM helix 3	111..141	CDD:320224	8/29 (28%)
		TM helix 4	153..173	CDD:320224	5/20 (25%)
		TM helix 5	204..233	CDD:320224	6/28 (21%)
		TM helix 6	249..279	CDD:320224	9/29 (31%)
		TM helix 7	292..317	CDD:320224	9/24 (38%)
Npy1r	NP_001106828.1	7tmA_NPY1R	40..330	CDD:320517	80/300 (27%)
		TM helix 1	41..67	CDD:320517	7/25 (28%)
		TM helix 2	74..99	CDD:320517	12/24 (50%)
		TM helix 3	112..142	CDD:320517	8/29 (28%)
		TM helix 4	153..174	CDD:320517	5/20 (25%)
		TM helix 5	207..236	CDD:320517	6/28 (21%)
		TM helix 6	255..285	CDD:320517	9/29 (31%)
		TM helix 7	298..323	CDD:320517	10/28 (36%)