Protein Alignment AstA-R2 and Oprl1

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001305876.1
• Gene: Oprl1 / 29256
• RGDID: 68438
• Length: 396
• Species: Rattus norvegicus
• Alignment Length: 361
• Identity: 123/361 - (34%)
• Similarity: 192/361 - (53%)
• Gaps: 41/361 - (11%)

  Fly     3 NTTMLANISLNATRNEENITSFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNN 67
            |.|:..::.|||:.     ::|..    |.:..|   |||.:..| .|.|..||.||:.|::.:.
  Rat    26 NETVPHHLLLNASH-----SAFLP----LGLKVT---IVGLYLAV-CIGGLLGNCLVMYVILRHT 77

  Fly    68 NMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLM 132
            .|::.||:.|.|||.||.: |:|.:||..||.::.:||:|...|::|..:.....|.|.:||..|
  Rat    78 KMKTATNIYIFNLALADTL-VLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAM 141

  Fly   133 SIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTF- 196
            |:||::|:.||||:..:||.:......|.:|.:..||.||||......|:.:..:      |..
  Rat   142 SVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIE------CLVE 200

  Fly   197 --TTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRM---SKESQRGRKRVTR 256
              ...|:.|| .:.:..|:.|:::|::|||..|..||.||    .|||:   |:|..|..:|:||
  Rat   201 IPAPQDYWGP-VFAICIFLFSFIIPVLIISVCYSLMIRRL----RGVRLLSGSREKDRNLRRITR 260

  Fly   257 LVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFR 321
            ||:|||..|...|.|||:.:|::.|.| :..:.|.:.|......|.|.:||:||:|||||.|||:
  Rat   261 LVLVVVAVFVGCWTPVQVFVLVQGLGV-QPGSETAVAILRFCTALGYVNSCLNPILYAFLDENFK 324

  Fly   322 KAF---------YKAVNCSSRYQNYTSDLPPPRKTS 348
            ..|         ::.:..|.|.::...|:....|||
  Rat   325 ACFRKFCCASSLHREMQVSDRVRSIAKDVGLGCKTS 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	108/290 (37%)
		TM helix 1	40..66	CDD:320224	11/25 (44%)
		TM helix 2	73..99	CDD:320224	13/25 (52%)
		TM helix 3	111..141	CDD:320224	11/29 (38%)
		TM helix 4	153..173	CDD:320224	5/19 (26%)
		TM helix 5	204..233	CDD:320224	10/28 (36%)
		TM helix 6	249..279	CDD:320224	15/29 (52%)
		TM helix 7	292..317	CDD:320224	11/24 (46%)
Oprl1	NP_001305876.1	7tmA_NOFQ_opioid_R	49..327	CDD:320220	109/294 (37%)
		TM helix 1	50..76	CDD:320220	12/29 (41%)
		TM helix 2	83..109	CDD:320220	14/26 (54%)
		TM helix 3	120..150	CDD:320220	11/29 (38%)
		TM helix 4	162..184	CDD:320220	7/21 (33%)
		TM helix 5	209..238	CDD:320220	11/29 (38%)
		TM helix 6	253..283	CDD:320220	15/29 (52%)
		TM helix 7	295..320	CDD:320220	11/24 (46%)