Protein Alignment AstA-R2 and XCR1

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_005274.1
• Gene: XCR1 / 2829
• HGNCID: 1625
• Length: 333
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 85/327 - (25%)
• Similarity: 156/327 - (47%)
• Gaps: 49/327 - (14%)

  Fly    12 LNATRNEENITSFFTD--------EEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNNN 68
            :.::.|.|:.|.|:.|        :.|  :..||...|  .:.::.:....||.||:.|:|...:
Human     1 MESSGNPESTTFFYYDLQSQPCENQAW--VFATLATTV--LYCLVFLLSLVGNSLVLWVLVKYES 61

  Fly    69 MRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMS 133
            :.|.||:.|:||..:||:|..| :|...:.|. :.|..|.|.|:.:..:..::.::||:.|.:|:
Human    62 LESLTNIFILNLCLSDLVFACL-LPVWISPYH-WGWVLGDFLCKLLNMIFSISLYSSIFFLTIMT 124

  Fly   134 IDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVV---VDYDAKKNITYGMCT 195
            |.|:|:||.|:.:..:.|....::..:.:|:..::.|:.....|.|:   .||   ..:|:.:.:
Human   125 IHRYLSVVSPLSTLRVPTLRCRVLVTMAVWVASILSSILDTIFHKVLSSGCDY---SELTWYLTS 186

  Fly   196 FTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQRGRKRVTRLVVV 260
                      .||...|   :||.|.||...|:.::..|:|        ..|:| |.|..:|:..
Human   187 ----------VYQHNLF---FLLSLGIILFCYVEILRTLFR--------SRSKR-RHRTVKLIFA 229

  Fly   261 VVIAFASLWLPVQLILLLKSL---DVI---ETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSEN 319
            :|:|:...|.|....|.|::|   .:|   |.....:..:.: .:.||:|..|.||:||.|:...
Human   230 IVVAYFLSWGPYNFTLFLQTLFRTQIIRSCEAKQQLEYALLI-CRNLAFSHCCFNPVLYVFVGVK 293

  Fly   320 FR 321
            ||
Human   294 FR 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	77/292 (26%)
		TM helix 1	40..66	CDD:320224	7/25 (28%)
		TM helix 2	73..99	CDD:320224	10/25 (40%)
		TM helix 3	111..141	CDD:320224	8/29 (28%)
		TM helix 4	153..173	CDD:320224	2/19 (11%)
		TM helix 5	204..233	CDD:320224	9/28 (32%)
		TM helix 6	249..279	CDD:320224	9/29 (31%)
		TM helix 7	292..317	CDD:320224	9/24 (38%)
XCR1	NP_005274.1	7tmA_XCR1	32..298	CDD:341337	78/294 (27%)
		TM helix 1	32..59	CDD:341337	8/28 (29%)
		TM helix 2	66..91	CDD:341337	10/25 (40%)
		TM helix 3	102..132	CDD:341337	8/29 (28%)
		TM helix 4	144..166	CDD:341337	2/21 (10%)
		TM helix 5	182..211	CDD:341337	9/41 (22%)
		TM helix 6	218..248	CDD:341337	9/30 (30%)
		TM helix 7	266..291	CDD:341337	9/25 (36%)