Protein Alignment AstA-R2 and Sstr5

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_037014.2
• Gene: Sstr5 / 25354
• RGDID: 3765
• Length: 362
• Species: Rattus norvegicus
• Alignment Length: 366
• Identity: 117/366 - (31%)
• Similarity: 190/366 - (51%)
• Gaps: 32/366 - (8%)

  Fly     1 MENTTMLANISLNATRNEENITSFFTDEEWLAINGTLPW-----IVGFFFGVIAITGFFGNLLVI 60
            ||..::.:..|.||:.....      :..|..:....|.     :|...:.::...|..||.|||
  Rat     1 MEPLSLASTPSWNASAASSG------NHNWSLVGSASPMGARAVLVPVLYLLVCTVGLSGNTLVI 59

  Fly    61 LVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFAS 125
            .||:.:..|::.||:.|:|||.||::| :|.:||.||...|.|||:|.|.||.|..|..:..|.|
  Rat    60 YVVLRHAKMKTVTNVYILNLAVADVLF-MLGLPFLATQNAVSYWPFGSFLCRLVMTLDGINQFTS 123

  Fly   126 IYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNIT 190
            |:.|::||:||:||||||:||...|...:..:|...:|:..|::|:|:....||        ...
  Rat   124 IFCLMVMSVDRYLAVVHPLRSARWRRPRVAKMASAAVWVFSLLMSLPLLVFADV--------QEG 180

  Fly   191 YGMCTFTTNDFLGPRTYQVTFFISSYLL----PLMIISGLYMRMIMRLWRQGTGVRM-SKESQRG 250
            :|.|..:..:.:|  .:...|...:.:|    ||::|...|:.:::::  :..|:|: |...:|.
  Rat   181 WGTCNLSWPEPVG--LWGAAFITYTSVLGFFGPLLVICLCYLLIVVKV--KAAGMRVGSSRRRRS 241

  Fly   251 RKRVTRLVVVVVIAFASLWLPVQLILLLK-SLDVIETNTLTKLVIQVTAQTLAYSSSCINPLLYA 314
            .::|||:|||||:.|...|||..::.::. :..:.|..|...|...|.  .|:|::||.|||||.
  Rat   242 ERKVTRMVVVVVLVFVGCWLPFFIVNIVNLAFTLPEEPTSAGLYFFVV--VLSYANSCANPLLYG 304

  Fly   315 FLSENFRKAFYKAVNCSSRYQNYTSDLPPPRKTSCARTSTT 355
            |||:|||::|.|.:.....|....:|...||.....|...|
  Rat   305 FLSDNFRQSFRKVLCLRRGYGMEDADAIEPRPDKSGRPQAT 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	102/295 (35%)
		TM helix 1	40..66	CDD:320224	9/25 (36%)
		TM helix 2	73..99	CDD:320224	14/25 (56%)
		TM helix 3	111..141	CDD:320224	14/29 (48%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	6/32 (19%)
		TM helix 6	249..279	CDD:320224	13/29 (45%)
		TM helix 7	292..317	CDD:320224	12/24 (50%)
Sstr5	NP_037014.2	7tm_GPCRs	48..314	CDD:475119	101/280 (36%)
		TM helix 2	73..94	CDD:410628	11/21 (52%)
		TM helix 3	110..132	CDD:410628	8/21 (38%)
		TM helix 4	155..171	CDD:410628	4/15 (27%)
		TM helix 5	197..220	CDD:410628	5/22 (23%)
		TM helix 6	246..268	CDD:410628	11/21 (52%)
		TM helix 7	282..307	CDD:410628	12/26 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	330..362		5/16 (31%)