Protein Alignment AstA-R2 and Nmbr

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_036931.1
• Gene: Nmbr / 25264
• RGDID: 3181
• Length: 390
• Species: Rattus norvegicus
• Alignment Length: 364
• Identity: 101/364 - (27%)
• Similarity: 185/364 - (50%)
• Gaps: 27/364 - (7%)

  Fly     7 LANISLNATRNEENI------TSFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVF 65
            |.|:||....:|..:      ..|..|.:.......:..::...:.:|...|..||::::.:.:.
  Rat     6 LPNLSLPTEASESELEPEVWENDFLPDSDGTTAELVIRCVIPSLYLIIISVGLLGNIMLVKIFLT 70

  Fly    66 NNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLV 130
            |:.|||..|:.|.||||.||:.::.|:|..|:.|....|.:|:..|:.:..:.:.:...|::||.
  Rat    71 NSTMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWVFGKLGCKLIPAIQLTSVGVSVFTLT 135

  Fly   131 LMSIDRFLAVVHPIRSRMMRTENITL---IAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYG 192
            .:|.||:.|:|:|:.   |:|..:.|   :..|.:|:|.::::||.|...: |....:..|.::.
  Rat   136 ALSADRYRAIVNPMD---MQTSGVVLWTSLKAVGIWVVSVLLAVPEAVFSE-VARIGSSDNSSFT 196

  Fly   193 MC-TFTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQ-----GTGVRMSKESQRGR 251
            .| .:...|.|.|:.:.|..|:..:|:||:|||..|..:...|.|.     |.....:|:....|
  Rat   197 ACIPYPQTDELHPKIHSVLIFLVYFLIPLVIISIYYYHIAKTLIRSAHNLPGEYNEHTKKQMETR 261

  Fly   252 KRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETN-TLTKLVIQVTAQTLAYSSSCINPLLYAF 315
            ||:.::|:|.|..|...|.|..::.|.:|.:..|.: :|..:::.:.|:.|::|:||:||.....
  Rat   262 KRLAKIVLVFVGCFVFCWFPNHILYLYRSFNYKEIDPSLGHMIVTLVARVLSFSNSCVNPFALYL 326

  Fly   316 LSENFRKAFYKAVNCSSRYQNYTSDLPPPRKTSCARTST 354
            |||:|||.|...:.|..:  :|     |.|.||...:|:
  Rat   327 LSESFRKHFNSQLCCGQK--SY-----PERSTSYLLSSS 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	86/294 (29%)
		TM helix 1	40..66	CDD:320224	4/25 (16%)
		TM helix 2	73..99	CDD:320224	11/25 (44%)
		TM helix 3	111..141	CDD:320224	8/29 (28%)
		TM helix 4	153..173	CDD:320224	5/22 (23%)
		TM helix 5	204..233	CDD:320224	10/28 (36%)
		TM helix 6	249..279	CDD:320224	10/29 (34%)
		TM helix 7	292..317	CDD:320224	7/24 (29%)
Nmbr	NP_036931.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		5/13 (38%)
		7tm_GPCRs	44..335	CDD:475119	86/294 (29%)
		TM helix 1	46..70	CDD:410628	4/23 (17%)
		TM helix 2	79..101	CDD:410628	10/21 (48%)
		TM helix 3	117..139	CDD:410628	3/21 (14%)
		TM helix 4	162..178	CDD:410628	4/15 (27%)
		TM helix 5	210..233	CDD:410628	8/22 (36%)
		TM helix 6	265..287	CDD:410628	6/21 (29%)
		TM helix 7	303..328	CDD:410628	7/24 (29%)