Protein Alignment AstA-R2 and Grpr

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_036838.2
• Gene: Grpr / 24938
• RGDID: 2750
• Length: 384
• Species: Rattus norvegicus
• Alignment Length: 351
• Identity: 92/351 - (26%)
• Similarity: 176/351 - (50%)
• Gaps: 22/351 - (6%)

  Fly     9 NISLNATRNEENITSFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTT 73
            |.:.|.|.|...:.::|        :..:.:::...:|:|.:.|..||:.:|.:.....:||:..
  Rat    20 NNTFNQTLNPPKMDNWF--------HPGIIYVIPAVYGLIIVIGLIGNITLIKIFCTVKSMRNVP 76

  Fly    74 NLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFL 138
            ||.|.:||..||:.::.|.|..|:.|:...|.:||..|:.:.::.:.:...|::||..:|.||:.
  Rat    77 NLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYK 141

  Fly   139 AVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCT-FTTNDFL 202
            |:|.|:..:.........:....:|||.:::::|.|...|:...:....|.|:..|. :..::.|
  Rat   142 AIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFSDLHPFHVKDTNQTFISCAPYPHSNEL 206

  Fly   203 GPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMS-----KESQRGRKRVTRLVVVVV 262
            .|:.:.:..|:..|::||.|||..|..:...|.:....:.:.     |:....|||:.:.|:|.|
  Rat   207 HPKIHSMASFLVFYIIPLSIISVYYYFIARNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFV 271

  Fly   263 IAFASLWLPVQLILLLKSLDVIETNT-LTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYK 326
            ..||..|||..:|.|.:|....|.:| :...:..:.|:.||:::||:||.....||::|||.|..
  Rat   272 GLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFITSICARLLAFTNSCVNPFALYLLSKSFRKQFNT 336

  Fly   327 AVNC---SSRYQNYTSDLPPPRKTSC 349
            .:.|   |...:::::.    |.|:|
  Rat   337 QLLCCQPSLLNRSHSTG----RSTTC 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	81/291 (28%)
		TM helix 1	40..66	CDD:320224	6/25 (24%)
		TM helix 2	73..99	CDD:320224	10/25 (40%)
		TM helix 3	111..141	CDD:320224	8/29 (28%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	9/28 (32%)
		TM helix 6	249..279	CDD:320224	13/29 (45%)
		TM helix 7	292..317	CDD:320224	7/24 (29%)
Grpr	NP_036838.2	7tmA_GRPR	42..334	CDD:320252	81/291 (28%)
		TM helix 1	43..69	CDD:320252	6/25 (24%)
		TM helix 2	76..102	CDD:320252	10/25 (40%)
		TM helix 3	114..144	CDD:320252	8/29 (28%)
		TM helix 4	156..176	CDD:320252	3/19 (16%)
		TM helix 5	208..233	CDD:320252	9/24 (38%)
		TM helix 6	258..288	CDD:320252	13/29 (45%)
		TM helix 7	302..327	CDD:320252	7/24 (29%)