Protein Alignment AstA-R2 and Oprd1

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_036749.1
• Gene: Oprd1 / 24613
• RGDID: 3233
• Length: 372
• Species: Rattus norvegicus
• Alignment Length: 334
• Identity: 100/334 - (29%)
• Similarity: 169/334 - (50%)
• Gaps: 44/334 - (13%)

  Fly    45 FGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRF 109
            :..:...|..||:||:..:|....:::.||:.|.|||.||.: ....:||.:..|::..||:|..
  Rat    56 YSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADAL-ATSTLPFQSAKYLMETWPFGEL 119

  Fly   110 WCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPV- 173
            .|::|..:.....|.||:||.:||:||::||.||:::...||.....:..:.:|::...|.||:
  Rat   120 LCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIM 184

  Fly   174 --AFT--HDVVVDYDAKKNITYGMCTFTTNDFLGPRTY-----QVTFFISSYLLPLMIISGLYMR 229
              |.|  .|..|           :||.   .|..|..|     ::..|:.::::|::||:..|..
  Rat   185 VMAVTQPRDGAV-----------VCTL---QFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGL 235

  Fly   230 MIMRLWRQGTGVRM---SKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTK 291
            |::||    ..||:   |||..|..:|:||:|:|||.||...|.|:.:.:::.:|  ::.|....
  Rat   236 MLLRL----RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTL--VDINRRDP 294

  Fly   292 LVIQV--TAQTLAYSSSCINPLLYAFLSENFRKAFYKAVNCSSRYQNYTSDLPPPRK-------T 347
            ||:..  ....|.|::|.:||:|||||.|||::.|.:........|. ...|..||:       |
  Rat   295 LVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQE-PGSLRRPRQATARERVT 358

  Fly   348 SCARTSTTG 356
            :|..:...|
  Rat   359 ACTPSDGPG 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	92/293 (31%)
		TM helix 1	40..66	CDD:320224	6/20 (30%)
		TM helix 2	73..99	CDD:320224	10/25 (40%)
		TM helix 3	111..141	CDD:320224	12/29 (41%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	8/33 (24%)
		TM helix 6	249..279	CDD:320224	12/29 (41%)
		TM helix 7	292..317	CDD:320224	11/26 (42%)
Oprd1	NP_036749.1	7tmA_Delta_opioid_R	50..329	CDD:320217	92/293 (31%)
		TM helix 1	51..77	CDD:320217	6/20 (30%)
		TM helix 2	84..110	CDD:320217	10/26 (38%)
		TM helix 3	121..151	CDD:320217	12/29 (41%)
		TM helix 4	163..185	CDD:320217	4/21 (19%)
		TM helix 5	209..239	CDD:320217	6/29 (21%)
		TM helix 6	258..284	CDD:320217	11/25 (44%)
		TM helix 7	297..322	CDD:320217	9/24 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	340..372		7/29 (24%)