Protein Alignment AstA-R2 and Pgr15l

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001028533.1
• Gene: Pgr15l / 245526
• MGIID: 2676330
• Length: 456
• Species: Mus musculus
• Alignment Length: 344
• Identity: 92/344 - (26%)
• Similarity: 171/344 - (49%)
• Gaps: 37/344 - (10%)

  Fly     2 ENTTMLANI---SLN-ATRNEENITSFFTDEEWLAINGTL-PWIVG-----------FFFGVIAI 50
            ||.:.:.:|   |.| .|:|..||:|    .||....|:: .|:.|           |.:.||.:
Mouse    24 ENISWVPSIEDQSCNHTTQNGTNISS----AEWGGPTGSVRRWLGGNPHIMAKIVLTFAYAVIIV 84

  Fly    51 TGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQ 115
            ...|||.||..|.|.:..::.:|.|:|.|||.:|::.::|..||....::...|.:||..|...:
Mouse    85 ISLFGNSLVCQVFVKHKEIKKSTGLLIFNLAISDILIILLNSPFALARFLSGQWVFGRIMCHVSR 149

  Fly   116 YLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHD-- 178
            :....:...|..||:.:::||...::||::.|:..::.:.::|::  |.:.:.:::|.|...:
Mouse   150 FAQYCSLHVSTLTLMAVAMDRHRVILHPMKPRLTHSQCLFVVAMI--WSIAVFLALPHAIYQNLF 212

  Fly   179 --VVVDYDAKKNITYGMCTFTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQG--- 238
              |.:|.|.:   :|.:.:|.....|..:...:..||..|:|||::|...|..:..|||.|.
Mouse   213 TLVNMDGDTR---SYCLPSFPGPSILVSKYVDLGTFILLYILPLLVIVVTYSHLGKRLWIQNAIG 274

  Fly   239 -TGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQTLA 302
             ...|......:.||:..|:::::|:.||..|.|:...::|.|...:|.::    |:.......|
Mouse   275 DASARQLMAHYQKRKKSIRMLILIVLVFAVCWFPLNFYVVLISSAGVENDS----VLFYAFHWFA 335

  Fly   303 YSSSCINPLLYAFLSENFR 321
            .||:|.||.:|.:|:.:||
Mouse   336 MSSTCYNPFIYCWLNRSFR 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	79/302 (26%)
		TM helix 1	40..66	CDD:320224	11/36 (31%)
		TM helix 2	73..99	CDD:320224	10/25 (40%)
		TM helix 3	111..141	CDD:320224	6/29 (21%)
		TM helix 4	153..173	CDD:320224	2/19 (11%)
		TM helix 5	204..233	CDD:320224	8/28 (29%)
		TM helix 6	249..279	CDD:320224	8/29 (28%)
		TM helix 7	292..317	CDD:320224	8/24 (33%)
Pgr15l	NP_001028533.1	7tmA_GPR83	73..357	CDD:320511	77/291 (26%)
		TM helix 1	74..100	CDD:320511	10/25 (40%)
		TM helix 2	107..132	CDD:320511	10/24 (42%)
		TM helix 3	145..175	CDD:320511	6/29 (21%)
		TM helix 4	186..207	CDD:320511	3/22 (14%)
		TM helix 5	237..266	CDD:320511	8/28 (29%)
		TM helix 6	286..316	CDD:320511	8/29 (28%)
		TM helix 7	325..350	CDD:320511	8/28 (29%)