Protein Alignment AstA-R2 and Xcr1

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_035928.3
• Gene: Xcr1 / 23832
• MGIID: 1346338
• Length: 322
• Species: Mus musculus
• Alignment Length: 307
• Identity: 89/307 - (28%)
• Similarity: 150/307 - (48%)
• Gaps: 40/307 - (13%)

  Fly    19 ENITSFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAA 83
            ||...||:         |:..||  .:.::.:....||.||:.|:|...|:.|.||:.|:||..:
Mouse    19 ENNVIFFS---------TISTIV--LYSLVFLLSLVGNSLVLWVLVKYENLESLTNIFILNLCLS 72

  Fly    84 DLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRM 148
            ||||..|.....:..:.   |..|.|:|:....:..::.::||:.|.:|:|.|:|:||.||.:..
Mouse    73 DLMFSCLLPVLISAQWS---WFLGDFFCKFFNMIFGISLYSSIFFLTIMTIHRYLSVVSPISTLG 134

  Fly   149 MRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRTYQVTFFI 213
            :.|....::....:|...::.|:|.|..|. |:..:.|.:..:|        ||. ..||...|
Mouse   135 IHTLRCRVLVTSCVWAASILFSIPDAVFHK-VISLNCKYSEHHG--------FLA-SVYQHNIF- 188

  Fly   214 SSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLL 278
              :||.:.||...|::::..|:|         ...|.|.|..||:..||:|:...|.|..|.|.|
Mouse   189 --FLLSMGIILFCYVQILRTLFR---------TRSRQRHRTVRLIFTVVVAYFLSWAPYNLTLFL 242

  Fly   279 KSLDVIETN--TLTKL-VIQVTAQTLAYSSSCINPLLYAFLSENFRK 322
            |: .:|:.:  :|.:| :..:..:.||:|..|.||:||.|:...||:
Mouse   243 KT-GIIQQSCESLQQLDIAMIICRHLAFSHCCFNPVLYVFVGIKFRR 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	84/287 (29%)
		TM helix 1	40..66	CDD:320224	8/25 (32%)
		TM helix 2	73..99	CDD:320224	10/25 (40%)
		TM helix 3	111..141	CDD:320224	8/29 (28%)
		TM helix 4	153..173	CDD:320224	2/19 (11%)
		TM helix 5	204..233	CDD:320224	8/28 (29%)
		TM helix 6	249..279	CDD:320224	12/29 (41%)
		TM helix 7	292..317	CDD:320224	10/25 (40%)
Xcr1	NP_035928.3	7tm_GPCRs	28..290	CDD:475119	84/289 (29%)
		TM helix 1	30..54	CDD:341337	7/25 (28%)
		TM helix 2	63..84	CDD:341337	9/20 (45%)
		TM helix 3	98..120	CDD:341337	4/21 (19%)
		TM helix 4	143..159	CDD:341337	2/15 (13%)
		TM helix 5	178..201	CDD:341337	9/26 (35%)
		TM helix 6	219..241	CDD:341337	8/21 (38%)
		TM helix 7	258..283	CDD:341337	9/24 (38%)