Protein Alignment AstA-R2 and Ghsr

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: XP_017175002.1
• Gene: Ghsr / 208188
• MGIID: 2441906
• Length: 427
• Species: Mus musculus
• Alignment Length: 377
• Identity: 100/377 - (26%)
• Similarity: 171/377 - (45%)
• Gaps: 54/377 - (14%)

  Fly    13 NATRNEENITSFFTDEEWLAINGT------------LPWIVGFFFGVIA--ITGFFGNLLVILVV 63
            |||.:||...:...|.:|.|..|.            .|.:.|.....:|  :.|..||||.:|||
Mouse    66 NATPSEEPEPNVTLDLDWDASPGNDSLSDELLPLFPAPLLAGVTATCVALFVVGISGNLLTMLVV 130

  Fly    64 VFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYY-WPYGRFWCRSVQYLIVVTAFASIY 127
            .....:|:||||.:.::|.:||: :.||:|........|. |.:|...|:..|::.....:|::.
Mouse   131 SRFRELRTTTNLYLSSMAFSDLL-IFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVL 194

  Fly   128 TLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVP----VAFTHDVVVD-YDAKK 187
            |:..:|::|:.|:..|:|::::.|:....:.|:.:|.|....:.|    |...|:...| .|..:
Mouse   195 TITALSVERYFAICFPLRAKVVVTKGRVKLVILVIWAVAFCSAGPIFVLVGVEHENGTDPRDTNE 259

  Fly   188 ------NITYGMCTFTTNDFLGPRTYQVTFFISS--YLLPLMIISGLYMRMIMRLW-RQGTGVRM 243
                  .:..|:.|             |..::||  :.||:..::.||..:..:|| |:|.....
Mouse   260 CRATEFAVRSGLLT-------------VMVWVSSVFFFLPVFCLTVLYSLIGRKLWRRRGDAAVG 311

  Fly   244 SKESQRGRKRVTRLVVVVVIAFASLWLP--VQLILLLK-----SLDVIETNTLTKLVIQVTAQTL 301
            |....:..|:..:::.|||.||...|||  |...|..|     ||::.:.:....||..|    |
Mouse   312 SSLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFV----L 372

  Fly   302 AYSSSCINPLLYAFLSENFRKAFYKAVNCSSRYQNYTSDLPPPRKTSCARTS 353
            .|.|:.|||:||..:|:.:|.|.:|.:...|..|...|.|......:..::|
Mouse   373 FYLSAAINPILYNIMSKKYRVAVFKLLGFESFSQRKLSTLKDESSRAWTKSS 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	83/308 (27%)
		TM helix 1	40..66	CDD:320224	10/27 (37%)
		TM helix 2	73..99	CDD:320224	9/25 (36%)
		TM helix 3	111..141	CDD:320224	7/29 (24%)
		TM helix 4	153..173	CDD:320224	4/23 (17%)
		TM helix 5	204..233	CDD:320224	7/30 (23%)
		TM helix 6	249..279	CDD:320224	11/31 (35%)
		TM helix 7	292..317	CDD:320224	11/24 (46%)
Ghsr	XP_017175002.1	7tmA_GHSR	107..395	CDD:320259	83/305 (27%)
		TM helix 1	107..133	CDD:320259	10/25 (40%)
		TM helix 2	140..165	CDD:320259	9/25 (36%)
		TM helix 3	178..208	CDD:320259	7/29 (24%)
		TM helix 4	220..242	CDD:320259	4/21 (19%)
		TM helix 5	271..300	CDD:320259	8/41 (20%)
		TM helix 6	317..347	CDD:320259	10/29 (34%)
		TM helix 7	363..388	CDD:320259	11/28 (39%)