Protein Alignment AstA-R2 and Sstr5

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_035555.1
• Gene: Sstr5 / 20609
• MGIID: 894282
• Length: 362
• Species: Mus musculus
• Alignment Length: 357
• Identity: 117/357 - (32%)
• Similarity: 190/357 - (53%)
• Gaps: 26/357 - (7%)

  Fly    10 ISLNATRNEENITSFFTDEEWLAINGTLPW-----IVGFFFGVIAITGFFGNLLVILVVVFNNNM 69
            :||.:|.:.....:..:...|..::...|.     :|...:.::...|..||.|||.||:....|
Mouse     4 LSLTSTPSWNASAASSSSHNWSLVDPVSPMGARAVLVPVLYLLVCTVGLGGNTLVIYVVLRYAKM 68

  Fly    70 RSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSI 134
            ::.||:.|:|||.||::| :|.:||.||...|.|||:|.|.||.|..|..:..|.||:.|::||:
Mouse    69 KTVTNVYILNLAVADVLF-MLGLPFLATQNAVSYWPFGSFLCRLVMTLDGINQFTSIFCLMVMSV 132

  Fly   135 DRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTN 199
            ||:||||||:||...|...:..:|...:|:..|::|:|:....||        ...:|.|..:..
Mouse   133 DRYLAVVHPLRSARWRRPRVAKLASAAVWVFSLLMSLPLLVFADV--------QEGWGTCNLSWP 189

  Fly   200 DFLGPRTYQVTFFISSYLL----PLMIISGLYMRMIMRLWRQGTGVRM-SKESQRGRKRVTRLVV 259
            :.:|  .:...|...:.:|    ||::|...|:.:::::  :..|:|: |...:|..::|||:||
Mouse   190 EPVG--LWGAAFITYTSVLGFFGPLLVICLCYLLIVVKV--KAAGMRVGSSRRRRSERKVTRMVV 250

  Fly   260 VVVIAFASLWLPVQLILLLK-SLDVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKA 323
            |||:.|...|||..::.::. :..:.|..|...|...|.  .|:|::||.|||||.|||:|||::
Mouse   251 VVVLVFVGCWLPFFIVNIVNLAFTLPEEPTSAGLYFFVV--VLSYANSCANPLLYGFLSDNFRQS 313

  Fly   324 FYKAVNCSSRYQNYTSDLPPPRKTSCARTSTT 355
            |.||:.....|....:|...||.....|..||
Mouse   314 FRKALCLRRGYGVEDADAIEPRPDKSGRPQTT 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	102/295 (35%)
		TM helix 1	40..66	CDD:320224	9/25 (36%)
		TM helix 2	73..99	CDD:320224	14/25 (56%)
		TM helix 3	111..141	CDD:320224	14/29 (48%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	6/32 (19%)
		TM helix 6	249..279	CDD:320224	13/29 (45%)
		TM helix 7	292..317	CDD:320224	12/24 (50%)
Sstr5	NP_035555.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		3/19 (16%)
		7tm_GPCRs	48..314	CDD:475119	101/280 (36%)
		TM helix 2	73..94	CDD:410628	11/21 (52%)
		TM helix 3	110..132	CDD:410628	8/21 (38%)
		TM helix 4	155..171	CDD:410628	4/15 (27%)
		TM helix 5	197..220	CDD:410628	5/22 (23%)
		TM helix 6	246..268	CDD:410628	11/21 (52%)
		TM helix 7	282..307	CDD:410628	12/26 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	330..362		6/16 (38%)