Protein Alignment AstA-R2 and Sstr4

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_033245.2
• Gene: Sstr4 / 20608
• MGIID: 105372
• Length: 385
• Species: Mus musculus
• Alignment Length: 368
• Identity: 104/368 - (28%)
• Similarity: 183/368 - (49%)
• Gaps: 56/368 - (15%)

  Fly     1 MENTTMLANISLNATRNEENITSFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVF 65
            :|:||....|:.:...:||...:..:|....|...|:..|    :.::.:.|..||.|||.|::.
Mouse    11 VEDTTWTPGINASWAPDEEEEDAMGSDGTGTAGMVTIQCI----YALVCLVGLVGNALVIFVILR 71

  Fly    66 NNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLV 130
            ...|::.||:.::|||.||.:| :|.:||.|:...:.:||:|...||:|..:..:..|.|::.|.
Mouse    72 YAKMKTATNIYLLNLAVADELF-MLSVPFVASAAALRHWPFGAVLCRAVLSVDGLNMFTSVFCLT 135

  Fly   131 LMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCT 195
            ::|:||::|||||:|:...|..::..:..:.:|:..|:|::|:|    |..|....:......|.
Mouse   136 VLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIA----VFADTRPARGGEAVACN 196

  Fly   196 FTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRL--------WRQGTGVRMSKESQRGRK 252
            ...........:.:..|:..:|||::.|...|:.::.::        |:|         .:|..|
Mouse   197 LHWPHPAWSAVFVIYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQ---------RRRSEK 252

  Fly   253 RVTRLVVVVVIAFASLWLP---VQLI-LLLKSLDVIETNTLTKLVIQVTAQTLAYSSSCINPLLY 313
            ::||||::||..|...|:|   |||: |.:.|||.         .:...:..|:|::||.||:||
Mouse   253 KITRLVLMVVTVFVLCWMPFYVVQLLNLFVTSLDA---------TVNHVSLILSYANSCANPILY 308

  Fly   314 AFLSENFRKAFYKAVNCSSRYQNYTSDLPPPRKTSCARTSTTG 356
            .|||:|||::|.: |.|                ..|....|||
Mouse   309 GFLSDNFRRSFQR-VLC----------------LRCCLLETTG 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	88/296 (30%)
		TM helix 1	40..66	CDD:320224	8/25 (32%)
		TM helix 2	73..99	CDD:320224	12/25 (48%)
		TM helix 3	111..141	CDD:320224	10/29 (34%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	6/28 (21%)
		TM helix 6	249..279	CDD:320224	15/33 (45%)
		TM helix 7	292..317	CDD:320224	9/24 (38%)
Sstr4	NP_033245.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..37		6/25 (24%)
		7tmA_SSTR4	45..319	CDD:320639	89/300 (30%)
		TM helix 1	46..72	CDD:320639	9/29 (31%)
		TM helix 2	79..105	CDD:320639	12/26 (46%)
		TM helix 3	116..146	CDD:320639	10/29 (34%)
		TM helix 4	158..180	CDD:320639	5/25 (20%)
		TM helix 5	205..234	CDD:320639	6/28 (21%)
		TM helix 6	249..279	CDD:320639	14/29 (48%)
		TM helix 7	287..312	CDD:320639	9/33 (27%)