Protein Alignment AstA-R2 and npr-13

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_506659.2
• Gene: npr-13 / 191160
• WormBaseID: WBGene00013883
• Length: 450
• Species: Caenorhabditis elegans
• Alignment Length: 344
• Identity: 79/344 - (22%)
• Similarity: 164/344 - (47%)
• Gaps: 54/344 - (15%)

  Fly    10 ISLNATRNEENITSFFTDEEWLAI-NGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTT 73
            |.:||...:.|        :|..: ...|.:.|.:|  :|.|.|..||.|:|..::....: |..
 Worm    10 IDVNAILQQFN--------DWTVLFEVRLGYSVLYF--LILIIGLVGNGLLITSILMRKKL-SVA 63

  Fly    74 NLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFL 138
            |:.::|||.:||:..|..:|.|.....:..|.:|...|:.|......:...|.::|..::|||:.
 Worm    64 NIFLINLAVSDLLLCITAVPITPVLAFMKRWIFGIIMCKLVPTCQAFSVLISSWSLCYIAIDRYR 128

  Fly   139 AVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHD---VVVDYDAKKNITYGMCTFTTND 200
            ::|.|:|...  ::......::..|:|..:.|.|:.::.:   :|::     |:|  :|    .|
 Worm   129 SIVTPLREPW--SDRHARWLLMFTWVVAFLASYPLYYSQNLKTMVIE-----NVT--LC----GD 180

  Fly   201 FLG----------PRTYQVTFFISSYLLPLMIISGLYMRMIMRL---W--RQGTGVRMSKESQRG 250
            |.|          ..||..:..|...::|.:|:|..|:.::.::   |  .:|:.:..::::|..
 Worm   181 FCGEFNWQSDEISKLTYTTSLLIIQLIIPAIIMSFCYLMILQKVQTDWLVDEGSMLTAAQQAQTA 245

  Fly   251 --RKRVTRLVVVVVIAFASLWLPVQLILLLKSLDV-IE-TNTLTKLVIQ-------VTAQTLAYS 304
              ::||..:::::||.|.:.|.|:..:.|.:.|.: .| ..|:.|:::.       :....:|.:
 Worm   246 VRKRRVMYVLILMVIVFMACWFPLSAVNLFRDLGMRFEFCQTVYKVLMMDQMYFKLLNVHVIAMT 310

  Fly   305 SSCINPLLYAFLSENFRKA 323
            |...||:||.::|:..|:|
 Worm   311 SIVWNPVLYFWMSKRHRRA 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	73/314 (23%)
		TM helix 1	40..66	CDD:320224	9/25 (36%)
		TM helix 2	73..99	CDD:320224	9/25 (36%)
		TM helix 3	111..141	CDD:320224	7/29 (24%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	7/28 (25%)
		TM helix 6	249..279	CDD:320224	8/31 (26%)
		TM helix 7	292..317	CDD:320224	6/31 (19%)
npr-13	NP_506659.2	7tmA_NPYR-like	32..330	CDD:320331	73/314 (23%)
		TM helix 1	32..57	CDD:320331	9/26 (35%)
		TM helix 2	63..88	CDD:320331	9/24 (38%)
		TM helix 3	101..131	CDD:320331	7/29 (24%)
		TM helix 4	142..163	CDD:320331	4/20 (20%)
		TM helix 5	194..223	CDD:320331	7/28 (25%)
		TM helix 6	246..276	CDD:320331	8/29 (28%)
		TM helix 7	298..323	CDD:320331	6/24 (25%)