Protein Alignment AstA-R2 and npr-22

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001023541.1
• Gene: npr-22 / 190424
• WormBaseID: WBGene00022004
• Length: 434
• Species: Caenorhabditis elegans
• Alignment Length: 403
• Identity: 100/403 - (24%)
• Similarity: 184/403 - (45%)
• Gaps: 55/403 - (13%)

  Fly     4 TTMLANISLNAT----RNEENITSFFTDEEWLAINGTLP---WIVGFFFGVIAITGFFGNLLVIL 61
            :::|:.|:..|:    |||...|.....:|...|....|   .:...|:.::.:...:||:||||
 Worm     9 SSLLSRITTTASEIMMRNEPTTTENPAVQEMNHIYHLTPSMKMLCILFYSILCVCCVYGNVLVIL 73

  Fly    62 VVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVY---YWPYGRFWCRSVQYLIVVTAF 123
            |:|:...:|:.||::|:|||.|||:..:.||||:....::|   .|.:|...|..:.:|..:..|
 Worm    74 VIVYFKRLRTATNILILNLAVADLLISVFCIPFSYWQVLIYDDQRWLFGSMMCSLLAFLQAMAVF 138

  Fly   124 ASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKN 188
            .|.:|||::|.||::|::..:...:..|....|..:...||..:::::|:.||.....|.|...|
 Worm   139 LSAWTLVVISFDRWMAIMFLLTPNIRITRRRALYLVAATWIFSILMALPLLFTTRFFEDQDGLPN 203

  Fly   189 ITYGMCTFTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLW-------RQGTGVRMSKE 246
            .......|..:.....:.|.....|..|::|..::...|..:.:::|       :.|...:|..:
 Worm   204 CGENWTYFGDSGEQVRKVYSSMVLILQYVVPQAVLIITYTHIGIKMWNSRVPGMQNGATKKMIVD 268

  Fly   247 SQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSL-----DVIETNTLTKLVIQVTAQTLAYSSS 306
            .....|::..:|:::...||..|||  |::|:..:     |:.....:  |.:...|..||.|.|
 Worm   269 RHESVKKLVPMVILISALFALCWLP--LLILINVIPEFYPDINSWGYI--LYLWWFAHGLAMSHS 329

  Fly   307 CINPLLYAFLSENFRKAF------------YKAV-----NCSSRYQN----------YTSDLPPP 344
            .:||::|...:..||:.|            :|.:     |.|..::|          .:||..|
 Worm   330 MVNPIIYFIRNARFREGFCFFSSKLLPCISFKELRLLTDNTSRSFRNRSRFSGVINPTSSDEKP- 393

  Fly   345 RKTSCARTSTTGL 357
             .||..|.|.:|:
 Worm   394 -ATSLTRYSRSGV 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	77/299 (26%)
		TM helix 1	40..66	CDD:320224	9/25 (36%)
		TM helix 2	73..99	CDD:320224	13/25 (52%)
		TM helix 3	111..141	CDD:320224	11/29 (38%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	5/28 (18%)
		TM helix 6	249..279	CDD:320224	9/29 (31%)
		TM helix 7	292..317	CDD:320224	9/24 (38%)
npr-22	NP_001023541.1	7tmA_PR4-like	51..347	CDD:320514	77/299 (26%)
		TM helix 1	52..78	CDD:320514	9/25 (36%)
		TM helix 2	85..110	CDD:320514	13/24 (54%)
		TM helix 3	126..156	CDD:320514	11/29 (38%)
		TM helix 4	169..190	CDD:320514	4/20 (20%)
		TM helix 5	219..248	CDD:320514	5/28 (18%)
		TM helix 6	271..301	CDD:320514	9/31 (29%)
		TM helix 7	315..340	CDD:320514	9/24 (38%)