Protein Alignment AstA-R2 and npr-5

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001024265.1
• Gene: npr-5 / 190386
• WormBaseID: WBGene00021983
• Length: 433
• Species: Caenorhabditis elegans
• Alignment Length: 388
• Identity: 86/388 - (22%)
• Similarity: 167/388 - (43%)
• Gaps: 51/388 - (13%)

  Fly     1 MENTTMLANISLNATRNEENITSFFTDEEWLAING----TLPW----IVGFFFGVIAITGFFGNL 57
            :..||..:.|| |...:..|..|.....|.:|..|    |:.:    |..|.:|.:.:.|.|||.
 Worm    11 ISTTTTPSTIS-NVITSHSNNGSCIQIAEAIAAQGIDDITVDFYIRSIFTFLYGFLFVLGIFGNG 74

  Fly    58 LVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTA 122
            .|:..|..|..::|..|:.::||...||:.|...||.|....|...|.:|...|..|......:.
 Worm    75 GVLWAVARNKRLQSARNVFLLNLIFTDLILVFTAIPVTPWYAMTKDWAFGSVMCHLVPLSNSCSV 139

  Fly   123 FASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVP--VAFTHDVVVDYDA 185
            |.:.::|..:|:|:||.:..|.:..:...:.:.:..::  |||..::::|  ::|.|     .|.
 Worm   140 FVTSWSLTAISLDKFLHINDPTKQPVSIRQALAITFLI--WIVSTLINLPYLMSFEH-----VDG 197

  Fly   186 KKNITYGMCTF-----------TTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWR--- 236
            ...:..|...:           :.|   ..:.|..|..:..:::|:.:|:..|.:::.::.:
 Worm   198 SFYVQPGETPYCGHFCDEANWQSEN---SRKIYGTTVMLLQFVVPMAVITYCYFKILQKVSKDMI 259

  Fly   237 -------QGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTK--L 292
                   |....:...::...:|:|..:::.:|:.|...|||:.|:.|:|.... |...|.:  .
 Worm   260 IQNAQFCQSLTQKQRSDATSRKKKVNYILIAMVVTFIGCWLPLTLLNLVKDFKK-EPEWLKRQPF 323

  Fly   293 VIQVTAQTLAYSSSCINPLLYAFLS-ENFRKAFYKAVNCSSRYQNYTSDLPPPRKTSCARTST 354
            ...:.|..:|.|....||||:.:|: :..|....|.:|.:....::.|     |.::..|.||
 Worm   324 FWAINAHVIAMSLVVWNPLLFFWLTRKQKRSGLSKILNSTEIVSSFAS-----RVSNSIRRST 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	68/314 (22%)
		TM helix 1	40..66	CDD:320224	9/25 (36%)
		TM helix 2	73..99	CDD:320224	9/25 (36%)
		TM helix 3	111..141	CDD:320224	8/29 (28%)
		TM helix 4	153..173	CDD:320224	4/21 (19%)
		TM helix 5	204..233	CDD:320224	5/28 (18%)
		TM helix 6	249..279	CDD:320224	9/29 (31%)
		TM helix 7	292..317	CDD:320224	7/24 (29%)
npr-5	NP_001024265.1	7tmA_NPYR-like	56..347	CDD:320331	66/301 (22%)
		TM helix 1	57..83	CDD:320331	9/25 (36%)
		TM helix 2	90..115	CDD:320331	9/24 (38%)
		TM helix 3	128..158	CDD:320331	8/29 (28%)
		TM helix 4	169..190	CDD:320331	4/22 (18%)
		TM helix 5	224..253	CDD:320331	5/28 (18%)
		TM helix 6	279..309	CDD:320331	9/29 (31%)
		TM helix 7	323..347	CDD:320331	7/23 (30%)