DRSC/TRiP Functional Genomics Resources

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Protein Alignment AstA-R2 and npr-21

DIOPT Version :9

Sequence 1:NP_001263042.1 Gene:AstA-R2 / 43393 FlyBaseID:FBgn0039595 Length:357 Species:Drosophila melanogaster
Sequence 2:NP_510779.2 Gene:npr-21 / 188781 WormBaseID:WBGene00020727 Length:362 Species:Caenorhabditis elegans


Alignment Length:320 Identity:82/320 - (25%)
Similarity:146/320 - (45%) Gaps:52/320 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 VGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVY--- 102
            |.:.|  :.:....|||:::||......:||..|..:.||..|||...|.|:...|.:::..   
 Worm    18 VSYLF--VFLATIIGNLIILLVFFSQKRVRSVPNFFLANLTVADLFVGIFCVLQNAVNFVFQGHG 80

  Fly   103 YWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVL 167
            .||:|:..|.|..|::......|...|||:|::|.:||:.|:|.|...::.:.:.:...:|:...
 Worm    81 RWPFGKVLCYSYIYVLHFIPNVSAGILVLVSVERLIAVLRPLRVRRAFSQKVLITSSAVVWLTSA 145

  Fly   168 VVSVPVAFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRTYQVTF---FISSYLLPLMIISGLYM- 228
            |::.|.......:...|.  |.||.:||....:..|....::..   ||..|.:||:|:..:|. 
 Worm   146 VMNTPYVVASQFLEISDG--NETYTICTRRHVEIYGFNLLKLVATINFIVWYAVPLVILLCIYAT 208

  Fly   229 -----------------RMIMR-LWRQGT---GVRMSKESQRGRKRVTRLVVVVVIAFASLWLPV 272
                             :::.| .||...   ||.:.|     |::|.||.|.:|:|||...||.
 Worm   209 IGLVVSKAATITKHSANKLLPRSSWRSEASTGGVSVEK-----RRKVGRLAVGIVVAFAFFSLPR 268

  Fly   273 QLILLL---------KSLDVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKA 323
            .:..:.         :.|:.:::      |:|..:..|.:.::.::|.||||||..||::
 Worm   269 YVYFMWTVWRDPMAPRCLNCLQS------VLQPISFLLLFFNAAVDPFLYAFLSTRFRQS 322

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AstA-R2NP_001263042.1 7tm_4 47..>164 CDD:304433 33/119 (28%)
7tm_1 55..313 CDD:278431 72/294 (24%)
npr-21NP_510779.2 7tmA_Trissin_R 15..323 CDD:320140 82/320 (26%)
TM helix 1 16..40 CDD:320140 7/23 (30%)
TM helix 2 49..71 CDD:320140 8/21 (38%)
TM helix 3 90..112 CDD:320140 6/21 (29%)
TM helix 4 135..151 CDD:320140 2/15 (13%)
TM helix 5 184..207 CDD:320140 6/22 (27%)
TM helix 6 248..273 CDD:320140 10/24 (42%)
TM helix 7 291..316 CDD:320140 8/30 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1294084at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.920

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