Protein Alignment AstA-R2 and ckr-1

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_491918.3
• Gene: ckr-1 / 188774
• WormBaseID: WBGene00020712
• Length: 421
• Species: Caenorhabditis elegans
• Alignment Length: 405
• Identity: 98/405 - (24%)
• Similarity: 155/405 - (38%)
• Gaps: 114/405 - (28%)

  Fly    40 IVGFFFGVIAITGFFGNLLVILVVV-FNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYY 103
            ::...|.:..|....||.:|||.:: .::..||.||..::|||.|||:..|:|||.|....:...
 Worm    15 MISSIFLLCLILSLLGNAIVILTILGKSHRSRSITNFYLLNLAFADLLRSIICIPSTLLGELTQC 79

  Fly   104 WPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLV 168
            |..|...|:.|.:|..|...||.|||.:::|:|:.|:..|:.||..:|:...||.|..:|.....
 Worm    80 WLLGAAMCKIVAFLQPVGVCASAYTLAVIAIERYYAICRPLESRKWQTKKRALITISLVWCFSFS 144

  Fly   169 VSVPVAFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRT---YQVTFFISSYLLPLMIISGLYMRM 230
            .::...|.      |||...      .||.:...||..   ||:....:...:||.::.|||..:
 Worm   145 ANLTSLFL------YDANPG------KFTCDSTKGPLVDFIYQLYLTFTLLFVPLALMVGLYGNV 197

  Fly   231 IMRL----------------------------W------------------------------RQ 237
            |:.|                            |                              ..
 Worm   198 IITLNTAINSDHPTVEQQMIEKTLPSRASFSDWFVSAVQRVPSMKVVSKTFQFKEKNSLSIPQTS 262

  Fly   238 GTGVRMSKES-------QRG-------------------RKRVTRLVVVVVIAFASLWLPVQLIL 276
            |..||.|:.|       .||                   :|:|||:::.:||.||..|:|..|..
 Worm   263 GLSVRPSRSSFSSFFSTPRGSFDVTMLLRSTNQEKILIAKKKVTRMLITLVIVFAFCWVPSYLYW 327

  Fly   277 LLKSLDVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKAVNCSSRYQNYTSDL 341
            ||..:..:....|....:..:...:.|.||..||:.|.|::::||.:.  ...|.
 Worm   328 LLLRMAELAATDLWNPGLNSSLTIMTYISSLANPITYCFMNKSFRSSV--LAYCR---------- 380

  Fly   342 PPPRK--TSCARTST 354
            |.|::  |.|:...|
 Worm   381 PKPKRPLTRCSALPT 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	92/371 (25%)
		TM helix 1	40..66	CDD:320224	7/26 (27%)
		TM helix 2	73..99	CDD:320224	13/25 (52%)
		TM helix 3	111..141	CDD:320224	12/29 (41%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	9/31 (29%)
		TM helix 6	249..279	CDD:320224	14/48 (29%)
		TM helix 7	292..317	CDD:320224	7/24 (29%)
ckr-1	NP_491918.3	7tmA_CCKR-like	30..375	CDD:320124	90/356 (25%)
		TM helix 2	49..75	CDD:320124	13/25 (52%)
		TM helix 3	87..117	CDD:320124	12/29 (41%)
		TM helix 4	131..149	CDD:320124	4/17 (24%)
		TM helix 5	171..196	CDD:320124	7/24 (29%)
		TM helix 6	300..330	CDD:320124	12/29 (41%)
		TM helix 7	343..368	CDD:320124	7/24 (29%)