Protein Alignment AstA-R2 and npr-12

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001293732.1
• Gene: npr-12 / 188742
• WormBaseID: WBGene00020689
• Length: 397
• Species: Caenorhabditis elegans
• Alignment Length: 401
• Identity: 95/401 - (23%)
• Similarity: 171/401 - (42%)
• Gaps: 73/401 - (18%)

  Fly    10 ISLNATRNEENITSFFTDE--EWLA-----------INGTLPWIVGFFFGVIAITGFFGNLLVIL 61
            ::::.|....|.|..:|:.  :|.|           ||.....||. .:|::...|...|.:|:|
 Worm     1 MTVHKTMQPPNSTGQWTEIHCDWFAEMQNYQNSLYKINFDGSPIVP-MYGLVCSFGALANFIVLL 64

  Fly    62 VVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASI 126
            ..|...|:|:..|..|||||.:||:..::..|.|....:..:||:|.:.|:.:..:..|..|.|.
 Worm    65 AFVRTANLRNLRNSFIVNLAFSDLILCVVTAPVTLYTSLNLFWPFGDWSCKFLAGVQAVNTFVSS 129

  Fly   127 YTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFT-------HDVVVDYD 184
            .||..:::||.|..:.|:|.|:..|..:....:|  ||:.::|::|.|..       .|...|..
 Worm   130 LTLAFIAMDRVLLTLCPVRWRLAATAPLLCYGVV--WIISIIVALPYALAVSSKLAPFDPWSDRA 192

  Fly   185 AKKNITY----------GMCTFTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQG- 238
            ..|.:||          .|.....|..:...||........|:|||..::..|.::...:.::.
 Worm   193 TPKMLTYCNRQVPEICAEMQEAWDNAIVSKTTYTFVVLGIQYILPLAALAYAYFQIGSTIQKRSK 257

  Fly   239 ------TGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVT 297
                  |..||  :.|...:|...|:.::|:.:|..|.|:.:..:|..|::|..:.    .:.:.
 Worm   258 VSRTVDTTRRM--QMQNRNRRALLLLFLLVLTYAVCWAPMNIYHVLNGLEIINYSQ----NMYIF 316

  Fly   298 AQTLAYSSSCINPLLYAFLSENFRKAFYK---------------------AVNCSSRYQNYT--- 338
            ...:..||:|:||::||.::|:||.|...                     |.:.:|:.:|.|
 Worm   317 CHLVGISSTCVNPIVYALVNESFRNALQSMILQFRPCYVTTTGTAATNVYAYSATSKAENVTLMR 381

  Fly   339 ---SDLPPPRK 346
               |..|.|.:
 Worm   382 DPFSTTPRPNE 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	79/308 (26%)
		TM helix 1	40..66	CDD:320224	8/25 (32%)
		TM helix 2	73..99	CDD:320224	10/25 (40%)
		TM helix 3	111..141	CDD:320224	9/29 (31%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	7/28 (25%)
		TM helix 6	249..279	CDD:320224	6/29 (21%)
		TM helix 7	292..317	CDD:320224	7/24 (29%)
npr-12	NP_001293732.1	7tmA_NPYR-like	42..343	CDD:320331	79/309 (26%)
		TM helix 1	43..69	CDD:320331	8/26 (31%)
		TM helix 2	76..101	CDD:320331	10/24 (42%)
		TM helix 3	114..144	CDD:320331	9/29 (31%)
		TM helix 4	155..176	CDD:320331	5/22 (23%)
		TM helix 5	222..251	CDD:320331	7/28 (25%)
		TM helix 6	272..302	CDD:320331	6/29 (21%)
		TM helix 7	311..336	CDD:320331	7/28 (25%)