Protein Alignment AstA-R2 and npr-27

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_501164.2
• Gene: npr-27 / 185662
• WormBaseID: WBGene00018344
• Length: 366
• Species: Caenorhabditis elegans
• Alignment Length: 333
• Identity: 67/333 - (20%)
• Similarity: 144/333 - (43%)
• Gaps: 40/333 - (12%)

  Fly    47 VIAITGFFGNLLVILVVVFNNNMRS----------TTNLMIVNLAAADLMFVILCIPFTATDYMV 101
            |:.:.|..|||.:| ..:|...:.|          .:.:.|..||.:| ||::|.:|.||:....
 Worm    41 VVCLVGTPGNLWII-YKLFRAKLWSGASVQLTVSQRSRIYIFALACSD-MFLLLTLPATASYNYH 103

  Fly   102 YYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVV 166
            ..|.:|...|..::.:.:.....|:..|.:||::|::.|...:|.......::..:|:.|::.|:
 Worm   104 GTWIFGSAACYIIRSIEIFAKLFSVVLLTVMSLERYIIVCTRLRHIYRAWMSLVPLAVGTIFGVL 168

  Fly   167 LVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMI 231
            :...:...:.....|.:|  .::|:......:|:..  ..:....|:..:::|..|::..|:.::
 Worm   169 VPTIIHYFYLQHFSVPFD--PDVTWVCLPLMSNEVF--NLFAQYTFVVGFIIPFAIMTACYIMLV 229

  Fly   232 ------MRLWRQGTGVRMSKESQRGR------KRVTRLVVVVVIAFASLW----LP---VQLILL 277
                  .::.|..|...::|..:..|      |.:.|:.|...:.:|..|    ||   .|:...
 Worm   230 RHVRTKYKMRRAQTTTTLAKPGKEPRYMSEVKKSIWRIAVFHFVCWAPFWGFTMLPNYIYQIDQF 294

  Fly   278 LKSLDVIET--NTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKAVNCSSRYQNYTSD 340
            |...:..|:  .::..:..::.:..|.|.::..|.:|||.|:.:.||..|   |...:.:.:|..
 Worm   295 LHGDNEEESGGESIFLVYCRLVSNCLPYINAAGNWVLYALLNVDVRKHIY---NQPKKKRKFTLK 356

  Fly   341 LPPPRKTS 348
            ..|...:|
 Worm   357 FNPVNTSS 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	62/307 (20%)
		TM helix 1	40..66	CDD:320224	6/18 (33%)
		TM helix 2	73..99	CDD:320224	10/25 (40%)
		TM helix 3	111..141	CDD:320224	6/29 (21%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	4/34 (12%)
		TM helix 6	249..279	CDD:320224	9/42 (21%)
		TM helix 7	292..317	CDD:320224	6/24 (25%)
npr-27	NP_501164.2	7tm_classA_rhodopsin-like	35..336	CDD:410626	59/300 (20%)
		TM helix 1	35..60	CDD:410626	7/19 (37%)
		TM helix 2	76..101	CDD:410626	10/25 (40%)
		TM helix 3	113..143	CDD:410626	6/29 (21%)
		TM helix 4	159..177	CDD:410626	3/17 (18%)
		TM helix 5	202..227	CDD:410626	4/26 (15%)
		TM helix 6	255..285	CDD:410626	6/29 (21%)
		TM helix 7	296..336	CDD:410626	7/39 (18%)