Protein Alignment AstA-R2 and npr-6

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_509725.2
• Gene: npr-6 / 185623
• WormBaseID: WBGene00009619
• Length: 402
• Species: Caenorhabditis elegans
• Alignment Length: 309
• Identity: 84/309 - (27%)
• Similarity: 149/309 - (48%)
• Gaps: 34/309 - (11%)

  Fly    38 PWIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVY 102
            |:.:..:..|..:.. .||.||:.||:.|..|::.||:.|.|||.:|:|.....:..|.|...:.
 Worm    38 PFFISMYCAVFLVAS-SGNFLVVYVVMTNKRMQTITNIFITNLAVSDIMVNFTSLWLTPTYTSIG 101

  Fly   103 YWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVH-----PIRSRM-MRTENITLIAIVT 161
            :|.:|...|..:......:.|.|.:||..::|||::.:||     .|..|| ||:   .|..||.
 Worm   102 HWIFGGGLCHGLPLFQGTSIFISTWTLTAIAIDRYIVIVHNSSNININDRMSMRS---CLSFIVL 163

  Fly   162 LWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTF--TTNDFLGPR---TYQVTFFISSYLLPLM 221
            :|:..|::..|.|.        :.|.|..:..|.|  .:.|:....   .:.:...|..::||.:
 Worm   164 IWLCSLLLVTPYAI--------NMKLNYIHEPCDFLICSEDWSNAEFRSIFGIVVMILQFILPFV 220

  Fly   222 IISGLYMRMIMRLW-----RQGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSL 281
            :|:..|    :::|     ||....|  |...:.:||:.|:::|:|:.||..|.|..|:..|:.|
 Worm   221 LIAISY----IKIWLFLNSRQSMTER--KSDIKRKKRLLRMLIVMVVIFAICWFPFNLLNCLRDL 279

  Fly   282 DVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKAVNC 330
            .:..........:.::...::.:::..||:||||::|.||:.|.|.|.|
 Worm   280 KLDNFMRGYFSFVFLSVHLMSMTATAWNPILYAFMNETFREEFAKVVPC 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	79/300 (26%)
		TM helix 1	40..66	CDD:320224	7/25 (28%)
		TM helix 2	73..99	CDD:320224	10/25 (40%)
		TM helix 3	111..141	CDD:320224	8/29 (28%)
		TM helix 4	153..173	CDD:320224	5/19 (26%)
		TM helix 5	204..233	CDD:320224	5/31 (16%)
		TM helix 6	249..279	CDD:320224	10/29 (34%)
		TM helix 7	292..317	CDD:320224	6/24 (25%)
npr-6	NP_509725.2	7tmA_NPYR-like	39..322	CDD:320331	79/300 (26%)
		TM helix 1	39..65	CDD:320331	7/26 (27%)
		TM helix 2	72..97	CDD:320331	9/24 (38%)
		TM helix 3	110..140	CDD:320331	8/29 (28%)
		TM helix 4	156..177	CDD:320331	6/23 (26%)
		TM helix 5	203..232	CDD:320331	6/32 (19%)
		TM helix 6	247..277	CDD:320331	10/29 (34%)
		TM helix 7	290..315	CDD:320331	6/24 (25%)