Protein Alignment AstA-R2 and npr-7

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_509570.3
• Gene: npr-7 / 185321
• WormBaseID: WBGene00018067
• Length: 380
• Species: Caenorhabditis elegans
• Alignment Length: 327
• Identity: 81/327 - (24%)
• Similarity: 153/327 - (46%)
• Gaps: 37/327 - (11%)

  Fly    18 EENITSFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAA 82
            :.|:|.|..:...:.|...:..::...:|::......|||.|:|:|:....|::.||:.|.:::|
 Worm     4 DSNLTDFQCEYPAIDIGIHMKTLLAVGYGLVGALSLVGNLAVLLIVICRREMQTVTNIFISSVSA 68

  Fly    83 ADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASI----YTLVLMSIDRFLAVVHP 143
            |||:.....:..|...|....|.:|::.|    |::.:....|:    .||..:::||:..|..|
 Worm    69 ADLVITSFSLWATPLAYYQRVWHFGKYMC----YMVSIIQGLSLMWVPLTLAAVALDRYSLVASP 129

  Fly   144 IRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRTYQ 208
            .|..|  ::...|:.|..:|:....|..|:....|.|        .:||.|.|....:...:.:.
 Worm   130 FRQPM--SKKTCLLIIAGIWMGGFAVLSPMIRMVDFV--------DSYGPCHFCLESWDHDKQHY 184

  Fly   209 VTFFISSYL-----LPLMIISGLYMRMIMRL---------WRQGTGVRMSKESQRGRKRVTRLVV 259
            ..|:..|.|     :||::||..:.|:.:.|         .|..:.|..|.:.:| ::|:..|::
 Worm   185 RLFYGLSVLVIRSAIPLVLISLCHWRIAVILNTQTKKFQTLRSASTVTQSTDIRR-KQRLQTLLL 248

  Fly   260 VVVIAFASLWLPVQLILLLKSLDVI-ETNTLTKLV---IQVTAQTLAYSSSCINPLLYAFLSENF 320
            .:|:.||...||:.|..:|:.|.|: :...:...|   |.......|.:.:.:|||:||:.:|||
 Worm   249 AMVVIFAVSSLPLDLSNVLQDLIVVYQVRPVPDNVRHFIFFFCHWTAMAGTLLNPLVYAYYNENF 313

  Fly   321 RK 322
            |:
 Worm   314 RR 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	77/306 (25%)
		TM helix 1	40..66	CDD:320224	7/25 (28%)
		TM helix 2	73..99	CDD:320224	8/25 (32%)
		TM helix 3	111..141	CDD:320224	7/33 (21%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	8/33 (24%)
		TM helix 6	249..279	CDD:320224	9/29 (31%)
		TM helix 7	292..317	CDD:320224	8/27 (30%)
npr-7	NP_509570.3	7tmA_NPYR-like	25..317	CDD:320331	77/306 (25%)
		TM helix 1	26..52	CDD:320331	7/25 (28%)
		TM helix 2	59..84	CDD:320331	8/24 (33%)
		TM helix 3	97..127	CDD:320331	7/33 (21%)
		TM helix 4	138..159	CDD:320331	5/20 (25%)
		TM helix 5	185..214	CDD:320331	8/28 (29%)
		TM helix 6	238..268	CDD:320331	9/30 (30%)
		TM helix 7	285..310	CDD:320331	7/24 (29%)