Protein Alignment AstA-R2 and npr-33

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_510612.1
• Gene: npr-33 / 185141
• WormBaseID: WBGene00009278
• Length: 399
• Species: Caenorhabditis elegans
• Alignment Length: 408
• Identity: 95/408 - (23%)
• Similarity: 176/408 - (43%)
• Gaps: 75/408 - (18%)

  Fly     1 MENTTMLANISLNATRNEEN---------ITSFFTDE---EWLAINGTLPWIV-GFFFGVIAITG 52
            :|.||.:.|..|  |.||.:         |:...|..   :..:.:..|.:|| |..|.:|...|
 Worm    11 IEKTTEIVNSVL--TSNESDGVLEQTSTLISVLATQSAPLQCFSCHPKLYFIVFGLVFMIIICAG 73

  Fly    53 FFGNLLVILVVVFNNN-MRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQY 116
            ..||:.::.|::.:.. |.|:.|..::|||.|||..:|.|.|......:...|....|.|..:::
 Worm    74 VIGNIFIVFVILMDRKLMSSSVNQFLLNLAIADLGNLIFCSPDAILVLIDRGWLLPNFACHLLRF 138

  Fly   117 LIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVV 181
            |.....:||:...:.:.::||||:..|:|.:...|:. |:..:..:|.|....:.|. |.:..:|
 Worm   139 LQEYFLYASVLLQMAIGVERFLAICSPMRMQRFSTKT-TISVLAGVWCVAACFASPY-FLYQGIV 201

  Fly   182 DYDAK----KNITYGMCTFTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVR 242
            .:...    |.|::...|:          ::....|..|.:||:.::.||..|...||.......
 Worm   202 FHKLYFCFWKGISHKTRTY----------FKYCELIVLYAIPLVFLTTLYSIMCRVLWGNEDNHN 256

  Fly   243 MSKESQRG-----RKRVTRLVVVVVIAFASLWLPVQLILLL-KSLD-VIETNTLTKLVIQVTAQT 300
            ::..||:.     |:.|.:::::.::.:...:.|:|::.:| |.|| .::.....:|::.|
 Worm   257 IANHSQQEAILKLRRSVVKMLIISMLLYFLCYTPIQVLFMLEKILDHSVQLPQWLRLLLNV---- 317

  Fly   301 LAYSSSCINPLLYAFLSENFR----------------------KAFYKAVNCS-------SRYQN 336
            |:..||..||::|.....:||                      |:.|:.|:.|       |.|.:
 Worm   318 LSVMSSSTNPIVYIICCRHFRLRLRDVAAGISSFCCWLLPSFSKSEYECVDESMTAKLSRSPYVS 382

  Fly   337 YTSDLPPPRKTSCARTST 354
            :.|.   .|:.|.|..||
 Worm   383 FRSS---RRQNSRANLST 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	73/319 (23%)
		TM helix 1	40..66	CDD:320224	9/26 (35%)
		TM helix 2	73..99	CDD:320224	10/25 (40%)
		TM helix 3	111..141	CDD:320224	8/29 (28%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	7/28 (25%)
		TM helix 6	249..279	CDD:320224	5/35 (14%)
		TM helix 7	292..317	CDD:320224	8/24 (33%)
npr-33	NP_510612.1	7tm_classA_rhodopsin-like	62..334	CDD:410626	68/287 (24%)
		TM helix 1	62..87	CDD:410626	7/24 (29%)
		TM helix 2	94..121	CDD:410626	10/26 (38%)
		TM helix 3	133..163	CDD:410626	8/29 (28%)
		TM helix 4	175..194	CDD:410626	3/19 (16%)
		TM helix 5	218..243	CDD:410626	7/34 (21%)
		TM helix 6	268..298	CDD:410626	4/29 (14%)
		TM helix 7	309..334	CDD:410626	8/28 (29%)