Protein Alignment AstA-R2 and Oprk1

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001305664.1
• Gene: Oprk1 / 18387
• MGIID: 97439
• Length: 409
• Species: Mus musculus
• Alignment Length: 303
• Identity: 92/303 - (30%)
• Similarity: 161/303 - (53%)
• Gaps: 26/303 - (8%)

  Fly    33 INGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTAT 97
            |:..:|.|:...:.|:.:.|..||.||:.|::....|::.||:.|.|||.||.: |...:||.:.
Mouse    54 ISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADAL-VTTTMPFQSA 117

  Fly    98 DYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTL 162
            .|::..||:|...|:.|..:.....|.||:||.:||:||::||.||:::...||.....|..:.:
Mouse   118 VYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICI 182

  Fly   163 WIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTND--------FLGPRTYQVTFFISSYLLP 219
            |::...|.:...    |:.....::::....|:....|        |:     ::..|:.::::|
Mouse   183 WLLASSVGISAI----VLGGTKVREDVDVIECSLQFPDDEYSWWDLFM-----KICVFVFAFVIP 238

  Fly   220 LMIISGLYMRMIMRLWRQGTGVRM---SKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSL 281
            ::||...|..||:||    ..||:   |:|..|..:|:|:||:|||..|...|.|:.:.:|:::|
Mouse   239 VLIIIVCYTLMILRL----KSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEAL 299

  Fly   282 DVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAF 324
            .....:| ..|........|.|::|.:||:|||||.|||::.|
Mouse   300 GSTSHST-AALSSYYFCIALGYTNSSLNPVLYAFLDENFKRCF 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	89/295 (30%)
		TM helix 1	40..66	CDD:320224	8/25 (32%)
		TM helix 2	73..99	CDD:320224	11/25 (44%)
		TM helix 3	111..141	CDD:320224	12/29 (41%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	7/28 (25%)
		TM helix 6	249..279	CDD:320224	12/29 (41%)
		TM helix 7	292..317	CDD:320224	10/24 (42%)
Oprk1	NP_001305664.1	7tmA_Kappa_opioid_R	60..341	CDD:320219	89/295 (30%)
		TM helix 1	61..87	CDD:320219	8/25 (32%)
		TM helix 2	94..120	CDD:320219	11/26 (42%)
		TM helix 3	131..161	CDD:320219	12/29 (41%)
		TM helix 4	173..195	CDD:320219	3/25 (12%)
		TM helix 5	223..252	CDD:320219	8/33 (24%)
		TM helix 6	267..297	CDD:320219	12/29 (41%)
		TM helix 7	309..334	CDD:320219	10/24 (42%)