Protein Alignment AstA-R2 and Oprd1

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_038650.3
• Gene: Oprd1 / 18386
• MGIID: 97438
• Length: 372
• Species: Mus musculus
• Alignment Length: 324
• Identity: 94/324 - (29%)
• Similarity: 166/324 - (51%)
• Gaps: 24/324 - (7%)

  Fly    45 FGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRF 109
            :..:...|..||:||:..:|....:::.||:.|.|||.||.: ....:||.:..|::..||:|..
Mouse    56 YSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADAL-ATSTLPFQSAKYLMETWPFGEL 119

  Fly   110 WCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVA 174
            .|::|..:.....|.||:||.:||:||::||.||:::...||.....:..:.:|::...|.||:.
Mouse   120 LCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIM 184

  Fly   175 FTHDVVVDYDAKKNITYGMCTFTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGT 239
                |:.....:......|..|.:..:......::..|:.::::|::||:..|..|::||    .
Mouse   185 ----VMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL----R 241

  Fly   240 GVRM---SKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQV--TAQ 299
            .||:   |||..|..:|:||:|:|||.||...|.|:.:.:::.:|  ::.|....||:..  ...
Mouse   242 SVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTL--VDINRRDPLVVAALHLCI 304

  Fly   300 TLAYSSSCINPLLYAFLSENFRKAFYKAVNCSSRYQNYTSDLPPPRK-------TSCARTSTTG 356
            .|.|::|.:||:|||||.|||::.|.:........|. ...|..||:       |:|..:...|
Mouse   305 ALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQE-PGSLRRPRQATTRERVTACTPSDGPG 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	86/283 (30%)
		TM helix 1	40..66	CDD:320224	6/20 (30%)
		TM helix 2	73..99	CDD:320224	10/25 (40%)
		TM helix 3	111..141	CDD:320224	12/29 (41%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	6/28 (21%)
		TM helix 6	249..279	CDD:320224	12/29 (41%)
		TM helix 7	292..317	CDD:320224	11/26 (42%)
Oprd1	NP_038650.3	7tmA_Delta_opioid_R	50..329	CDD:320217	86/283 (30%)
		TM helix 1	51..77	CDD:320217	6/20 (30%)
		TM helix 2	84..110	CDD:320217	10/26 (38%)
		TM helix 3	121..151	CDD:320217	12/29 (41%)
		TM helix 4	163..185	CDD:320217	4/25 (16%)
		TM helix 5	209..239	CDD:320217	6/29 (21%)
		TM helix 6	258..284	CDD:320217	11/25 (44%)
		TM helix 7	297..322	CDD:320217	9/24 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	340..372		7/29 (24%)