Protein Alignment AstA-R2 and npr-11

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_508234.2
• Gene: npr-11 / 182921
• WormBaseID: WBGene00016110
• Length: 402
• Species: Caenorhabditis elegans
• Alignment Length: 327
• Identity: 91/327 - (27%)
• Similarity: 159/327 - (48%)
• Gaps: 31/327 - (9%)

  Fly    21 ITSFFTDEEWLAINGT------LPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVN 79
            |..||.|::  .||||      ..:.:.|.:.:|.:.|..||.|.|:||:.|..||:|.|..|:|
 Worm    18 INYFFRDDQ--VINGTEYSPKEFGYFITFAYMLIILFGAIGNFLTIIVVILNPAMRTTRNFFILN 80

  Fly    80 LAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPI 144
            ||.:|....|:..|.|....:..:||:.|..|:....|.....|.|.:::..:::||::.::.|
 Worm    81 LALSDFFVCIVTAPTTLYTVLYMFWPFSRTLCKIAGSLQGFNIFLSTFSIASIAVDRYVLIIFP- 144

  Fly   145 RSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVV-VDYDAKKNITYGMCTFTTND-----FLG 203
             ::..|.:|::....:.:|::.|:::||:....|:. |..:...::...:| ...|:     .:.
 Worm   145 -TKRERQQNLSFCFFIMIWVISLILAVPLLQASDLTPVFVEPSCDLALYIC-HEQNEIWEKMIIS 207

  Fly   204 PRTYQVTFFISSYLLPLMIISGLYMRMIMRLW-----RQGTGVRMSKESQRGRKRVTR------L 257
            ..||.:...|:.|..||..:...|.|:..|:.     |.......:..|||.|..|.|      |
 Worm   208 KGTYTLAVLITQYAFPLFSLVFAYSRIAHRMKLRFANRNQNVTTNTNTSQRRRSVVERQRRTHLL 272

  Fly   258 VVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRK 322
            :|.||..||..|||:.:..:..:.:::.:.::|...|   ...||..|:|:|||:|||.:.|||.
 Worm   273 LVCVVAVFAVAWLPLNVFHIFNTFELVNSFSVTTFSI---CHCLAMCSACLNPLIYAFFNHNFRI 334

  Fly   323 AF 324
            .|
 Worm   335 EF 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	82/301 (27%)
		TM helix 1	40..66	CDD:320224	9/25 (36%)
		TM helix 2	73..99	CDD:320224	9/25 (36%)
		TM helix 3	111..141	CDD:320224	6/29 (21%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	8/28 (29%)
		TM helix 6	249..279	CDD:320224	13/35 (37%)
		TM helix 7	292..317	CDD:320224	11/24 (46%)
npr-11	NP_508234.2	7tmA_NPYR-like	40..336	CDD:320331	82/301 (27%)
		TM helix 1	41..67	CDD:320331	9/25 (36%)
		TM helix 2	74..99	CDD:320331	9/24 (38%)
		TM helix 3	112..142	CDD:320331	6/29 (21%)
		TM helix 4	153..174	CDD:320331	4/20 (20%)
		TM helix 5	208..237	CDD:320331	8/28 (29%)
		TM helix 6	264..294	CDD:320331	10/29 (34%)
		TM helix 7	304..329	CDD:320331	12/27 (44%)