Protein Alignment AstA-R2 and npr-3

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_502162.1
• Gene: npr-3 / 182494
• WormBaseID: WBGene00007006
• Length: 376
• Species: Caenorhabditis elegans
• Alignment Length: 345
• Identity: 79/345 - (22%)
• Similarity: 148/345 - (42%)
• Gaps: 41/345 - (11%)

  Fly    40 IVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYW 104
            |....:.::.:....||.||:.|:.||....|...:.:..||.:||:..:..:|.||.......|
 Worm    27 IFSLLYLLVWVGAIVGNTLVLYVLTFNQVSLSVRTVFVGCLAGSDLLMCLFSLPITAISIFSRVW 91

  Fly   105 PYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVV 169
            .:...:|:.:......|.|.|.:||.::::||.:.::.| ...::.......| :..:|::...:
 Worm    92 VFPAIFCKLIGVFQGGTIFVSSFTLTVIALDRCVLILRP-NQEIVNFPRAVFI-VFCIWLLGYSL 154

  Fly   170 SVPVAFTHDVVVDYDAKKNITYGMCTFTTNDFLGP--------RTYQVTFFISSYLLPLMIISGL 226
            ::||....|:.| ||   .|....|.....|| .|        |.|.::..:..:.:|.:|.|..
 Worm   155 ALPVGIYSDIAV-YD---EICGTFCEENWPDF-NPDTGRSGIRRAYGLSVLVLQFGIPALISSIC 214

  Fly   227 YMRMIMRLW------RQGTGVRMSKESQ--RGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDV 283
            |. ||.|:.      |:|..:|...|::  ..:.|..|:::|:|:.|...|:|...:.|.:.|..
 Worm   215 YW-MISRVMSDQLARRRGHNIRPESETKLVNRKTRANRMMIVMVVGFVLAWMPFNAVNLYRDLFG 278

  Fly   284 IETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKA-------------FYKAVNCSSRYQ 335
            |.....|...:   ....|..|:.:||::|::.:..||::             ..|....:|:..
 Worm   279 ISKWYSTVFAL---CHVCAMCSAVLNPIIYSWFNPQFRQSITTLFKGTDEARLIKKKPQSTSKMV 340

  Fly   336 NYTSDLPPPRK-TSCARTST 354
            :|.::....|| |..|.|.|
 Worm   341 SYPTNFSEIRKETEIASTKT 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	70/312 (22%)
		TM helix 1	40..66	CDD:320224	6/25 (24%)
		TM helix 2	73..99	CDD:320224	7/25 (28%)
		TM helix 3	111..141	CDD:320224	8/29 (28%)
		TM helix 4	153..173	CDD:320224	2/19 (11%)
		TM helix 5	204..233	CDD:320224	9/36 (25%)
		TM helix 6	249..279	CDD:320224	8/29 (28%)
		TM helix 7	292..317	CDD:320224	5/24 (21%)
npr-3	NP_502162.1	7tmA_NPYR-like	26..314	CDD:320331	69/297 (23%)
		TM helix 1	27..53	CDD:320331	6/25 (24%)
		TM helix 2	60..85	CDD:320331	7/24 (29%)
		TM helix 3	98..128	CDD:320331	8/29 (28%)
		TM helix 4	139..160	CDD:320331	4/21 (19%)
		TM helix 5	192..221	CDD:320331	8/29 (28%)
		TM helix 6	244..274	CDD:320331	8/29 (28%)
		TM helix 7	284..309	CDD:320331	6/27 (22%)