Protein Alignment AstA-R2 and Ntsr2

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_032773.2
• Gene: Ntsr2 / 18217
• MGIID: 108018
• Length: 416
• Species: Mus musculus
• Alignment Length: 366
• Identity: 83/366 - (22%)
• Similarity: 157/366 - (42%)
• Gaps: 63/366 - (17%)

  Fly    45 FGVIAITGFFGNLLVILVVVFNNNMR-STTNLMIVNLAAADLMFVILCIPFTATDYM--VYYWPY 106
            :.:|...|..||.|.:.||:.....| ......:::||.:.|:.:::.:|....:::  .|.|.:
Mouse    39 YSLIFALGTAGNALSVHVVLKARAGRPGRLRYHVLSLALSALLLLLISVPMELYNFVWSHYPWVF 103

  Fly   107 GRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSV 171
            |...||...::..:.|:|::.::..:|.:|.|||..|:|:|.:.|...|...:..:|:..|.:::
Mouse   104 GDLGCRGYYFVRELCAYATVLSVASLSAERCLAVCQPLRARRLLTPRRTRRLLSLVWVASLGLAL 168

  Fly   172 PVAF----THDVVVDYDAKKNITYGMCTFTTNDFLGPRTYQVTFFIS---SYLLPLMI---ISGL 226
            |:|.    .|: :...|.:......:||.    .:...|.||...::   |::|||.:   ::|:
Mouse   169 PMAVIMGQKHE-MERADGEPEPASRVCTV----LVSRATLQVFIQVNVLVSFVLPLALTAFLNGI 228

  Fly   227 YMRMIMRL-------------------------------WR-------QGTGVRMSKESQ-RGRK 252
            .:..::.|                               ||       |.:.||....|| |..:
Mouse   229 TVNHLVALYSQVPSASAQVNSIPSRLELLSEEGLLGFITWRKTLSLGVQASLVRHKDASQIRSLQ 293

  Fly   253 RVTRLVVVVVIAFASLWLPVQLILLLKSL--DVIETNTLTKL--VIQVTAQTLAYSSSCINPLLY 313
            ...:::..:|..:...|||.....|:...  |...|:.|...  ...:...||.|.||.:.|:||
Mouse   294 HSAQVLRAIVAVYVICWLPYHARRLMYCYIPDDGWTDELYDFYHYFYMVTNTLFYVSSAVTPVLY 358

  Fly   314 AFLSENFRKAFYKAVNCSSRYQNYTSDLPPPRKTSCARTST 354
            ..:|.:|||.|.:::  ||......|.:|.|::...:.|||
Mouse   359 NAVSSSFRKLFLESL--SSLCGEQRSVVPLPQEAPESTTST 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	74/334 (22%)
		TM helix 1	40..66	CDD:320224	7/20 (35%)
		TM helix 2	73..99	CDD:320224	4/25 (16%)
		TM helix 3	111..141	CDD:320224	8/29 (28%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	8/34 (24%)
		TM helix 6	249..279	CDD:320224	6/29 (21%)
		TM helix 7	292..317	CDD:320224	8/26 (31%)
Ntsr2	NP_032773.2	7tm_GPCRs	33..369	CDD:475119	74/334 (22%)
		TM helix 1	35..59	CDD:320478	7/19 (37%)
		TM helix 2	69..91	CDD:320478	4/21 (19%)
		TM helix 3	109..131	CDD:320478	3/21 (14%)
		TM helix 4	154..170	CDD:320478	2/15 (13%)
		TM helix 5	204..227	CDD:320478	6/22 (27%)
		TM helix 6	296..318	CDD:320478	4/21 (19%)
		TM helix 7	337..362	CDD:320478	8/24 (33%)