Protein Alignment AstA-R2 and Npy6r

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_035065.1
• Gene: Npy6r / 18169
• MGIID: 1098590
• Length: 371
• Species: Mus musculus
• Alignment Length: 358
• Identity: 93/358 - (25%)
• Similarity: 171/358 - (47%)
• Gaps: 56/358 - (15%)

  Fly    13 NATRNEENITSFFTDEE----WLAINGTLPWIVGFFFGVIAITGFFGNL-LVILVVVFNNNMRST 72
            |.|..:.|.::||..|.    :|||     .::...:.||.|.|.|||| |:|::.......::.
Mouse    11 NKTSGKSNNSAFFYFESCQPPFLAI-----LLLLIAYTVILIMGIFGNLSLIIIIFKKQREAQNV 70

  Fly    73 TNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRF 137
            ||::|.||:.:|::..::|||||....::.:|.:|...|:...|:..|:...||::|||::|:|:
Mouse    71 TNILIANLSLSDILVCVMCIPFTVIYTLMDHWVFGNTMCKLTSYVQSVSVSVSIFSLVLIAIERY 135

  Fly   138 LAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPV-------------------AFTHDVVVDY 183
            ..:|:| |....|..: ....|:.:|::.|.:|:|:                   .:||.|.
Mouse   136 QLIVNP-RGWKPRVAH-AYWGIILIWLISLTLSIPLFLSYHLTNEPFHNLSLPTDIYTHQVA--- 195

  Fly   184 DAKKNITYGMCTFTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQ 248
                      |.......|....:..:.|:..|.:||..|...|:::::.|.::...|...||::
Mouse   196 ----------CVEIWPSKLNQLLFSTSLFMLQYFVPLGFILICYLKIVLCLRKRTRQVDRRKENK 250

  Fly   249 ---RGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLT---KLVIQVTAQTLAYSSSC 307
               ...|||..:::.:|:.|.:.|||:.:..::  .|......::   .||. |....:|..|:|
Mouse   251 SRLNENKRVNVMLISIVVTFGACWLPLNIFNVI--FDWYHEMLMSCHHDLVF-VVCHLIAMVSTC 312

  Fly   308 INPLLYAFLSENFRKAFYKAVN---CSSRYQNY 337
            ||||.|.||::||:|.....::   |....::|
Mouse   313 INPLFYGFLNKNFQKDLMMLIHHCWCGEPQESY 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	82/310 (26%)
		TM helix 1	40..66	CDD:320224	10/26 (38%)
		TM helix 2	73..99	CDD:320224	11/25 (44%)
		TM helix 3	111..141	CDD:320224	10/29 (34%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	6/28 (21%)
		TM helix 6	249..279	CDD:320224	8/29 (28%)
		TM helix 7	292..317	CDD:320224	12/24 (50%)
Npy6r	NP_035065.1	7tm_GPCRs	42..329	CDD:475119	82/304 (27%)
		TM helix 1	42..63	CDD:320518	10/20 (50%)
		TM helix 2	72..94	CDD:320518	9/21 (43%)
		TM helix 3	110..132	CDD:320518	7/21 (33%)
		TM helix 4	153..169	CDD:320518	4/15 (27%)
		TM helix 5	207..230	CDD:320518	5/22 (23%)
		TM helix 6	260..282	CDD:320518	5/21 (24%)
		TM helix 7	297..322	CDD:320518	12/25 (48%)