Protein Alignment AstA-R2 and npr-28

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_509416.2
• Gene: npr-28 / 181089
• WormBaseID: WBGene00018886
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 410
• Identity: 92/410 - (22%)
• Similarity: 165/410 - (40%)
• Gaps: 71/410 - (17%)

  Fly     1 MENTTMLANISLNATRNEENITSFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVV- 64
            :.:|::|..:|   |.....|.....|.  :.|...:.::: ..:..:|:||..||..|::.|:
 Worm     6 ISSTSILTTVS---TTTSSTIVPSLNDP--MEIQFEIMFVM-VLYSCLAVTGVGGNCWVLIKVIK 64

  Fly    65 ------------FNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYL 117
                        :...::|:..:.::.|:..|| |.::.:|...||..|.::|:|.:.|:...:.
 Worm    65 QLSGCSSNRSRPYKTVVQSSAYVYLIILSVVDL-FSLIPVPMIVTDVYVNHFPFGLWACKLSYFC 128

  Fly   118 IVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVA--FTHDVV 180
            ..:....|...|..:|:||::||.|| ....:||...:|..:...:.|.|:..:||.  .|..|:
 Worm   129 EAINKSLSPMVLTALSVDRYIAVCHP-TLYWLRTTKFSLGVLAVCFSVSLIFIIPVTKKATMQVM 192

  Fly   181 VDYDAKKNITYGMCTFTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMSK 245
            .|...::.|   .|.|...| .....:.....|..||:||.||..:|:.::.:|:.......:.|
 Worm   193 KDNTDEEII---KCAFDHGD-SASYVFDTAQAIVCYLVPLFIICAVYLAILHKLFIHTRFSTVGK 253

  Fly   246 ESQRGRKRVTRLVVVVVIAFASLWLP---VQLILLLKSLDVIETN-----TLTKLVIQVTAQ--- 299
            ::.....||.:..|:||..:...|.|   :::..|:...  ||||     |:...|:...|:
 Worm   254 KTSISLGRVVKCSVMVVAFYFICWTPYWTMRIHYLVTRF--IETNSDGNSTVIDEVVAAVAEEVQ 316

  Fly   300 -----------------------------TLAYSSSCINPLLYAFLSENFRKAFYKAVNCSSRYQ 335
                                         :|.|:.|..|.|.|:||:.|.|.  .......:|..
 Worm   317 DGIETSYFFGLISKKRMHNIEIALIYILHSLTYAQSAFNWLFYSFLNRNLRS--NNGRGNGTRSA 379

  Fly   336 NYTSDLPPPRKTSCARTSTT 355
            ..||.......||...||.|
 Worm   380 ANTSVFDNGNATSTVNTSLT 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	77/339 (23%)
		TM helix 1	40..66	CDD:320224	7/38 (18%)
		TM helix 2	73..99	CDD:320224	6/25 (24%)
		TM helix 3	111..141	CDD:320224	7/29 (24%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	8/28 (29%)
		TM helix 6	249..279	CDD:320224	8/32 (25%)
		TM helix 7	292..317	CDD:320224	9/56 (16%)
npr-28	NP_509416.2	7tm_classA_rhodopsin-like	41..363	CDD:410626	74/330 (22%)
		TM helix 1	41..72	CDD:410626	7/31 (23%)
		TM helix 2	85..110	CDD:410626	6/25 (24%)
		TM helix 3	122..152	CDD:410626	7/29 (24%)
		TM helix 4	164..183	CDD:410626	3/18 (17%)
		TM helix 5	212..237	CDD:410626	8/24 (33%)
		TM helix 6	257..287	CDD:410626	7/29 (24%)
		TM helix 7	338..363	CDD:410626	7/24 (29%)