Protein Alignment AstA-R2 and npr-25

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_505883.1
• Gene: npr-25 / 179570
• WormBaseID: WBGene00011381
• Length: 376
• Species: Caenorhabditis elegans
• Alignment Length: 369
• Identity: 81/369 - (21%)
• Similarity: 154/369 - (41%)
• Gaps: 71/369 - (19%)

  Fly    37 LPWIVGFFFGVIAITGFFGNLLVILVVVF-NNNMRST------TNLMIVNLAAADLMFVILCIPF 94
            :|:.:.|.||.:      ||..|:..|.| ..:::|:      |.:.||.|.|.||: |.:.|||
 Worm    25 IPYSICFVFGTL------GNTAVLSYVFFITRSLKSSVTALGNTFIYIVALCAVDLL-VTVSIPF 82

  Fly    95 TATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSR---MMRTENI-T 155
            :.:..::..|.:|...|:....|.:.....|.:.|..::.||::|:.||...|   |..|..| |
 Worm    83 SLSYMILNNWVFGELVCKIHFMLELSNKMCSTFILTALAFDRYMAICHPEIKRIHEMRHTIYITT 147

  Fly   156 LIAIVTLWIV-VLVVSVPVAF-------------THDVVVDYDAKKNITYGMCTFTTNDFLGPRT 206
            ::|.::|::: .:|:|..|..             .|:|:     ::....||.       |..:.
 Worm   148 ILATLSLFLISPVVLSARVTSFKSGQYFVSAKNERHEVI-----RQMCIDGMA-------LEWKV 200

  Fly   207 YQVTFFI-SSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWL 270
            :...|.| .::|||..:::..|.::::||.||.   |...:|:...:|:|...:.....:.|..:
 Worm   201 WVSAFLIFFAFLLPCTLLTYFYAKIVLRLRRQR---RTMLQSRIPLRRITIYTMAATFFYLSCHI 262

  Fly   271 PVQLILLLKSLDVIETNTLTKLVIQVT--AQTLAYSSSCINPLLYAFLSENFRKAFY-------- 325
            |..|..:......:..:.:...|:..|  :..|.:.|:..|.:.||.|:..|:|...
 Worm   263 PFWLPQIYNIFSTVLGHKMNPKVMTFTYYSHLLPFISAAFNWIFYARLNSQFKKGLVLVTERMIR 327

  Fly   326 -------------KAVNCSSRYQNYTSDLPPPRKTSCARTSTTG 356
                         .||..:|::.:.....|........|:|:.|
 Worm   328 KRTKSMHEKGYSEAAVELTSKFDDVPLMCPHCEAQLSIRSSSNG 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	73/312 (23%)
		TM helix 1	40..66	CDD:320224	8/26 (31%)
		TM helix 2	73..99	CDD:320224	11/25 (44%)
		TM helix 3	111..141	CDD:320224	7/29 (24%)
		TM helix 4	153..173	CDD:320224	6/21 (29%)
		TM helix 5	204..233	CDD:320224	6/29 (21%)
		TM helix 6	249..279	CDD:320224	5/29 (17%)
		TM helix 7	292..317	CDD:320224	7/26 (27%)
npr-25	NP_505883.1	7tm_classA_rhodopsin-like	24..311	CDD:410626	71/307 (23%)
		TM helix 1	24..49	CDD:410626	9/29 (31%)
		TM helix 2	62..87	CDD:410626	11/25 (44%)
		TM helix 3	99..129	CDD:410626	7/29 (24%)
		TM helix 4	141..160	CDD:410626	5/18 (28%)
		TM helix 5	199..224	CDD:410626	6/24 (25%)
		TM helix 6	244..271	CDD:410626	5/26 (19%)
		TM helix 7	286..311	CDD:410626	6/24 (25%)