Protein Alignment AstA-R2 and tkr-3

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001343603.1
• Gene: tkr-3 / 177285
• WormBaseID: WBGene00006428
• Length: 400
• Species: Caenorhabditis elegans
• Alignment Length: 363
• Identity: 87/363 - (23%)
• Similarity: 159/363 - (43%)
• Gaps: 28/363 - (7%)

  Fly     4 TTMLANISLNATRNEENITSFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNNN 68
            ||::....:.|...|..::.   |:::..:......|....:.:||.....|||||:.:.:|...
 Worm    15 TTVIGGAGVLAEAGEAELSG---DDDFYELTPVELIIWCMLYAIIAFMAVVGNLLVLYITLFRLR 76

  Fly    69 MRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMS 133
            :||.|...|:||..|||...|..|||.....:...|...|..||.|.|:..|....|::|||..:
 Worm    77 VRSITTYFILNLGFADLFTGIFAIPFKFQAALFQEWFLPRSLCRIVPYVETVALTVSVFTLVTSA 141

  Fly   134 IDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTT 198
            :..|..:.....|:|  :.......::.:||:.::||:|....|: ..::....|.:...|....
 Worm   142 VHEFRTMFFSKCSQM--SPRSAKRCVLLIWIMAVLVSLPHGLFHN-TYEFPDDNNTSIVQCLPVY 203

  Fly   199 NDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQRGRKRVT-------- 255
            .|....:||.|...|..|.:|::|:...|..:.:::|..........|::...::::
 Worm   204 PDAGWWKTYNVYLVIIQYFVPMIILDTAYTMIAVKIWSLSQSRVELDETKMATQKISVVSMVSPN 268

  Fly   256 -------RLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKL-VIQVTAQTLAYSSSCINPLL 312
                   |.:::||..|:..|.|::..|||..|.. |.|....: ::...:..||.|:||:||::
 Worm   269 TQLSQLMRTLIIVVACFSLCWFPLETYLLLNELKP-EINGWKYINLVFFFSHWLAMSNSCLNPII 332

  Fly   313 YAF----LSENFRKAFYKAVNCSSRYQNYTSDLPPPRK 346
            |..    .:|.:|:.| :.:.|..:.|....|...|.:
 Worm   333 YGLYNTKYNEEYRRLF-RQIGCIWQRQKSLDDSMKPER 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	77/304 (25%)
		TM helix 1	40..66	CDD:320224	8/25 (32%)
		TM helix 2	73..99	CDD:320224	11/25 (44%)
		TM helix 3	111..141	CDD:320224	10/29 (34%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	8/28 (29%)
		TM helix 6	249..279	CDD:320224	8/44 (18%)
		TM helix 7	292..317	CDD:320224	8/29 (28%)
tkr-3	NP_001343603.1	7tm_GPCRs	47..344	CDD:475119	76/300 (25%)
		TM helix 1	49..73	CDD:320515	7/23 (30%)
		TM helix 2	82..104	CDD:320515	10/21 (48%)
		TM helix 3	120..142	CDD:320515	8/21 (38%)
		TM helix 4	163..179	CDD:320515	4/15 (27%)
		TM helix 5	210..233	CDD:320515	7/22 (32%)
		TM helix 6	275..297	CDD:320515	6/21 (29%)
		TM helix 7	312..337	CDD:320515	8/24 (33%)